Ch. 4: The Methods and Ethics of Research

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Ch. 4 of Garrett 6e Brain and Behavior

38 Terms

1

Ablation

Removal of brain tissue.

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2

Adoption Study

A technique for studying the roles of heredity and environment by comparing the similarity of adopted children to their biological parents with their similarity to their adoptive parents.

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3

Antisense RNA

A technology that temporarily disables a targeted gene or reduces its effectiveness.

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4

Autoradiography

A technique for identifying brain structures involved in an activity using a radioactive substance absorbed by more active neurons.

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5

Computed Tomography (CT)

An imaging technique that produces a series of X-rays taken from different angles.

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6

Concordance Rate

The proportion of cases in which a pair of related individuals shares a characteristic.

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7

Correlation

The degree to which two variables are related, measured by the correlation coefficient.

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8

Correlational Study

A study determining whether two variables are related without controlling an independent variable.

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9

Deception

In research, failing to tell participants the exact purpose of the research.

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10

Diffusion Tensor Imaging (DTI)

A variant of MRI that measures movement of water molecules to image brain pathways.

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11

Electroencephalogram (EEG)

A measure of brain activity recorded from electrodes on the scalp.

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12

Event-Related Potential

An EEG technique for measuring the brain’s responses to brief stimulation.

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13

Experimental Study

A study in which the researcher manipulates an independent variable.

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14

Fabrication

Deliberately falsifying, altering, or manipulating data or results in research.

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15

Family Study

A technique for studying heredity and environment by assessing shared characteristics among relatives.

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16

Functional Magnetic Resonance Imaging (fMRI)

A brain-imaging procedure measuring brain activation through blood flow changes.

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17

Gene Therapy

Treatment of a disorder by manipulating genes.

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18

Genetic Engineering

Manipulation of an organism’s genes or their functioning.

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19

Gene Transfer

Insertion of a gene from another organism into a recipient’s cells.

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20

Golgi Stain

A staining method that randomly stains about 5% of neurons for individual visibility.

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21

Immunocytochemistry

A procedure for labeling cellular components using a dye attached to an antibody.

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22

Informed Consent

Voluntary agreement to participate in a study after receiving full information.

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23

In Situ Hybridization

A procedure for locating gene activity using complementary radioactive DNA strands.

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24

Knockdown Technique

A genetic engineering technique that reduces a gene’s activity.

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25

Knockout Technique

A genetic engineering technique inserting a nonfunctioning gene mutation.

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26

Lesioning

Surgical damage to neural tissue using various methods.

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27

Magnetic Resonance Imaging (MRI)

An imaging technique measuring radio-frequency waves to form detailed images.

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28

Messenger Ribonucleic Acid (mRNA)

A copy of DNA that moves out of the nucleus to direct protein construction.

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29

Myelin Stain

A staining method that identifies neural pathways by staining fatty axon insulation.

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30

Nissl Stain

A staining method that stains cell bodies.

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31

Plagiarism

The theft or unauthorized use of another’s work or ideas.

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32

Positron Emission Tomography (PET)

An imaging technique revealing brain function by measuring radioactive substance uptake.

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33

Scanning Electron Microscope

A microscope that forms a three-dimensional image using emitted electrons.

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34

Stereotaxic Instrument

A device for precise positioning in the brain of an electrode or device.

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35

Theory

A system of statements that explains some phenomenon by integrating observations.

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36

Transcranial Magnetic Stimulation (TMS)

A noninvasive stimulation technique using a magnetic coil on brain tissue.

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37

Transmission Electron Microscope

A magnification system forming images by passing electrons through a tissue slice.

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38

Twin Studies

A technique for studying heredity and environment by assessing similarity between twins.

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