What is replication and where does it happen (2+1)
Creating a copy
Forming a leading and lagging strand
In the nucleus
What direction does DNA polymerase cream rage new DNA strand in
5’-3’, one nucleotide at a time
What is the 5’ end
Phosphate end
What is the 3’ end
Deoxyribose end
How does DNA run
Antiparallel (opposite directions to each other)
What is the enzyme that separates the strands of DNA
DNA helicase
What bonds hold the two strands together
Hydrogen bonds
Which enzyme allows DNA polymerase to bond
DNA primase
Which end does DNA primase attach
3’ end (nearest helicase in lagging strand)
How is the new strand of DNA made in the leading strand (3)
Continuously in a 5’-3’ direction using complementary bases
How is the new strand held to the old strand
Hydrogen bonds
How are lagging strands
In Okazaki fragments
How are Okazaki fragments attached together
DNA ligase seals the gaps in the sugar phosphate backbone with phosphodiester bonds