advance neuro lec 13

bg

grp of subcortical nuclei

motor control bg

provide regualtory control over voluntary movement

norm bg

help to appropriatly initiate and terminate movments

bg  function

help to org patterns of motor activity into established routines, habitual and automatic behavior

architecture of bg

form functional loops from the cortex to bg and back to cortex

allows it to change activity in cortex based upon evaluatio calc in bg

internal processing of bg

straitium- caudate and putamen

globus pallidus - internal and external

subthalamic nuclei

thalamus

substantia niagra

modulates bg

caudate/putamen

receive input form all over the cortex and the thalamus

motivation decsiion making motor planning

also receive da from SNpc

medium spiny neruons msn

resdient neruons in striatium

msn

respond to da but are gabergic

direct pthway

permits intended movements

facillitator accelerator

activaiton of msn in direct pthway stim movement

indirect pthway

suppresses inappropraite movement

suppressor brakes

activaiton of MSN in indirect pthway inhibtis movement

bg circuitry

control motor mvoemetn is achieved thorugh balance and appropriate targeting of indirect and direct 

input form balnk that stim direct pathway can overide the suppression by blank

cortex

indirect pthway and stim movement

da

stim movement from both direct and indirect pthway

more da = more movement less da = less movmenet

da to striatium comes form 

snc

direct pthway msn

express d1 receptors= excititatory

promote disinhibition of thalamus

indirect pthway msn

express d2 receptors = inhib

promot inhib of thalamus

cerebellum

recieves sensory info produces motor output

cerebellum funct

balance

posture

coordination

fine movment

meidate motor learning procedural memeory

some cognitive process