Central Nervous System
brain and spinal cord, body's decision maker
Peripheral Nervous System
includes somatic and autonomic nervous systems; the sensory and motor neurons that connect the central nervous system to the rest of the body
Somatic Nervous System
(skeletal nervous system) the division of the peripheral nervous system that controls the body's skeletal muscles
Autonomic Nervous System
the part of the peripheral nervous system that controls the glands and the muscles of the internal organs (such as the heart). Its sympathetic division arouses; its parasympathetic division calms.
Sympathetic Nervous System
mobilizing its energy and prepares body for action in stressful situations; fight or flight; releases adrenaline, increases heart rate
Parasympathetic Nervous System
relaxes and calms you down, rest and digest
Sensory Neurons
neurons that carry incoming information from the sensory receptors to the brain and spinal cord; messages come from outside —> into body —> to brain
Interneurons
neurons within the brain and spinal cord that communicate internally and intervene between the sensory inputs and motor outputs
Motor Neurons
Carry outgoing information from the brain and spinal cord to the muscles and glands; messages sent —> out
neuron
individual nerve cells in nervous systems that recieve, integrate, and transmit info
dendrite
parts of a neuron that receives info
Soma (cell body)
contains the nucleus and much of cells normal organs
axon and axon terminals
A long, thin fiber that carries electrical impulses away from the neuron's cell body; The branches at the end of an axon transmit signals to other neurons or target cells.
myelin sheath
Insulating material encasing the fibers some axons; enables vastly greater transmission speed of neural impulses as the impulse hops from one node to the next; damage leads to multiple sclerosis
nodes of ranvier
gaps in the myelin sheath
Reuptake
neurotransmitters are absorbed back into the neuron after they’ve been released; Descending neuron fires NT → goes through receptor site and ions enter → gets reabsorbed by ascending neuron
depolarization
The process during the action potential when Na+ is rushing into the cell causing the interior to become more positive; negatively charged neuron becomes positive
action potential
a neural impulse; a brief electrical charge that travels down an axon (+40mV)
threshold
the level of stimulation required to trigger a neural impulse (-55mV)
all-or-nothing principle
a neuron's reaction of either firing or not firing; all action potentials are the same strength; if the neuron fires, it will always fire at the same intensity. 100% each time
refractory period
recharging phase; when a neuron, after firing, cannot generate another action potential; momentarily drops below -70mV then returns to resting state
acetylcholine (ACh)
excitatory; enables muscle (motor) action, learning, and memory; Excess —> muscle cramps, confusion agitation; Lack —> memory problems, Alzheimer’s, muscle weakness; ACH being inhibited —> myasthenia gravis
dopamine
inhibitory; influences movement, learning, attention, emotion, reward systems; Excess —> hallucinations, impulsivity, schizophrenia; Lack —> Depression, Parkinson’s (tremors, slow movement)
serotonin
inhibitory; Affects mood, hunger, sleep, and arousal; created by sun; Excess —> agitation, rapid heart rate; Lack —> Depression, anxiety, sleep issues
norepinephrine
excitatory; helps control alertness and arousal, fight or flight state (sympathetic nervous system activation); Excess —> anxiety, high blood pressure, hyperactivity, (mania phase for bpd); Lack —> depression, low energy, poor focus
GABA
major inhibitory neurotransmitter; stops messages; Excess —> drowsiness, cognitive impairment; Lack —> anxiety, insomnia, seizures, Huntington’s disease
Glutamate
Excitatory neurotransmitter; involved in memory, thinking, learning; opposite of GABA; Excess —> neuron damage, anxiety, hyperactivity; Lack —> cognitive decline, learning issues
Endorphins
inhibitory; pain control and to pleasure; brain’s natural aspirin; drugs like morphine/opioids mimic this; Excess —> euphoria, reduced pain sensitivity (addiction); Lack —> Depression, increased pain sensitivity
agonist
mimics the action of a NT; increase effect of neurotransmitter; ex: meth mimics action of dopamine
antagonist
opposes / blocks the action (connections) of a NT; slow down effects
The Brainstem
responsible for automatic survival functions; connects cerebrum to spinal cord and cerebellum
Medulla
in the hindbrain, (brainstem), attaches to the spinal cord, controls unconscious functions; blood pressure, respiration, heart rate; if damaged —> likely dying / close to death
Thalamus (forebrain)
primary relay station for all senses except smell; neural messages —> this —> cerebral cortex; handles incoming and outgoing signals; damage—>synesthesia (tasting words); also associated with memory and emotion, like hearing a song and associating a memory with it
Reticular Activating System / Formation - RAS
central core of the brainstem; oversees alertness, arousal (heightened body systems), and attention processes; if damaged —> coma
Cerebellum (hindbrain)
back of the brainstem; coordination of movement, sense of equilibrium, balance
amygdala (limbic system)(forebrain)
involved in memory and emotion, particularly fear and anger; warns us when somethings wrong or scary; messages go faster to this than to prefrontal cortex
hypothalamus (limbic system)(forebrain)
regulator of biological needs (homeostasis), links endocrine system via the pituitary gland to brain, 4 biological drives: food, fight, flight, fornication
hippocampus (limbic system)(forebrain)
Memories are processed / formed through this part and then sent to various parts of cerebral cortex and stored as long term memory
cerebral cortex
The intricate fabric of interconnected neural cells covering the cerebral hemispheres; the body's ultimate control and information-processing center; higher brain functions (occipital, parietal, temporal, frontal lobe)
glial cells (nervous system)
support, nourish, and protect neurons; ex-schwann cells; gluey substance that speeds up process, helps repair damaged axons
frontal lobe (Cerebral Cortex)
planning, reasoning, working memory, paying attention, solving problems, and performing movements; contains broca’s area, motor cortex, prefrontal cortex
motor cortex (frontal lobe)
an area at the rear of the frontal lobes that controls voluntary movements
broca's area (frontal lobe)
in left frontal lobe, deals with speech production
Parietal Lobe (Cerebral Cortex)
Deals with sensory perception → how brains interprets what we are sensing; Visual and spatial relations; handles somatosensory info, receives info about temperature, pressure, texture, and pain; contains somatosensory cortex
Somatosensory Cortex (parietal lobe)
area at the front of the parietal lobes that registers and processes body touch and movement sensations; messages being recieved
Wernicke's area
in left temporal lobe, deals with speech interpretation / language comprehension
Occipital lobe (Cerebral Cortex)
Primary visual cortex; Receives and processes visual information
Visual Cortex (occipital lobe)
conscious processing of sights
Temporal lobe (Cerebral Cortex)
hearing and balance; memory, smell, motivation, emotion; recognizing faces (right hemisphere); contains auditory cortex, Wernicke’s area
Auditory Cortex (temporal lobe)
the area of the temporal lobe responsible for processing sound information
Association Areas
involved in higher mental functions such as learning, remembering, thinking, and speaking; an area of the cerebral cortex that functions in linking and coordinating the sensory and motor areas and relating the info the past experiences
Plasticity
ability of the brain to modify its structure/function following changes within the body or in the external environment, brain’s ability to rewire itself after damage
Neurogenesis
the formation of new neurons
Corpus Callosum
the large band of neural fibers connecting the two brain hemispheres and carrying messages between them
Split Brain
a condition resulting from surgery that isolates the brain's two hemispheres by cutting the fibers (mainly those of the corpus callosum) connecting them; Researcher Roger Sperry discovered brain specialization for the right and left through SAIL while Michael Gazzinga did a study on patients that have undergone split-brain surgery and revealed brain lateralization of functions
Left Hemisphere Functions
speech and language (Wernicke’s and Broca’s area), sequential processing, analytic thought, logic, science, math; contralateral representation
Right Hemisphere Functions
Spatial functions, patterns, visual configurations, color discrimination, musical functions, contralateral representation
adrenal glands
inner part helps trigger the fight or flight response; secretes epinephrine in times of stress
heredity
genetic transmission of traits and characteristics from parents to their offspring
Endocrine System
glands that secrete chemicals into the bloodstream that help control bodily functioning (in charge of the adrenaline effect)
Hormones (Endocrine System)
chemical messengers; travel through body much slower than neurotransmitters; regulate many physical and behavioral functions
Pituitary Gland (In Hypothalamus)
master gland of entire endocrine system; Stress, growth, reproduction; Signals other glands of the endocrine system to secrete hormones
Resting Potential
neuron is at rest (-70mV) and capable of generating action potential; if resting potential rises above threshold (-55mV), an action potential starts to travel from cell body down axon
Broca’s Aphasia
can’t produce speech
Wernicke’s Aphasia
can’t comprehend language
Hindbrain
contains medulla and cerebellum
Forebrain
Cerebral cortex, limbic system
midbrain
contains an area integrating sensory processes (vision and hearing), dopamine center of the brain
Limbic System (forebrain)
behavioral and emotional responses; associated with emotion and motivation; under cerebral cortex, above brainstem
EEG
Electroencephalograph; measures brain waves/electrical activity; seen a lot in sleep studies; measures brain activity
PET Scan
radioactive glucose to see functioning of the brain or where is activity occuring in the brain
MRI
magnets/radio waves to see structure of the soft tissue
fMRI
measures brain activity by detecting associated changes in blood flow, shows structure and function; mix of mri and pet
genetic predisposition
to be susceptible to it or more likely to encounter it due to inherited genes
evolutionary perspective
based on Charles Darwin's theory of natural selection
eugenics
the selection of desired heritable characteristics in order to improve future generations, typically in reference to humans
twin, family, adoption studies
observe nature vs nurture. ex. minnesota twins study
reflex arc
neurological and sensory mechanism that controls a reflex, an immediate response to a particular stimulus, message sent to spine
neural transmission
neuron firing
multiple sclerosis
caused by demyelination; ranges from fatigue to inability to walk, disease in which the body’s immune system can affect nerves in central nervous system
Myasthenia gravis
neurological disorder where one can’t contract their muscles; ACH is being inhibited
Excitatory neurotransmitters
tell second neuron to keep action potential going
Inhibitory neurotransmitters
not firing, stop action potential and stop message
substance P
deals with body’s pain perception; transmission of pain signals to the brain
adrenaline
energy; alertness and physical readiness; secreted by adrenal glands
leptin
energy balance by inhibiting hunger; secreted by fat cells; can affect mood and emotions, motivations related to eating behaviors; more leptin = less hungry; long term regulation of body weight
ghrelin
hunger hormone; produced in stomach and will signal brain to stimulate appetite; more ghrelin = more hungry
melatonin
sleep hormone; secreted based on darkness; sense light —> melatonin go down
oxytocin
love hormone; released in response to forms of social interaction and bonding; ex: childbirth or breastfeeding
psychoactive drugs
Chemicals that change the chemistry of the brain, altering perception and mental process through: chemical - blood/brain barrier, mental set - you get what you expect, environment - get more drunk at higher elevations
reuptake inhibitors
prevent a neurotransmitter from being reabsorbed by presynaptic axons
stimulant
euphoric feeling; ex: caffeine, nicotine, MDMA (ecstasy), PCP, cocaine, phetamines (meth), amphetamines (adderall); love = 150 units of dopamine, meth = 1250 units
depressants
slow down heart rate; ex: Alcohol, barbiturates, tranquilizers, anti-anxiety, valium; develop withdrawal symptoms
hallucinogens
change perception of reality, sensory (visual, auditory, tactile) hallucinations, loss of identity (dissociation); ex: (psychedelics) LSD, Mescaline (Peyote), mushrooms, marijuana; Tend to stay in system longer than other types of drugs
opiates
Agonists for endorphins (mimic) —> Reduce levels of GABA = slows down release of dopamine; Powerful painkillers and mood elevators; Drowsiness and euphoria due to artificially increasing dopamine levels; ex: Opium, morphine, heroin, methadone, codeine, oxycontin; highly physically addictive
tolerance
Diminished effect of the drug with the same dosage; Reverse —> Less of the drug to get the same type of effect, Ex. hallucinogens (Don’t leave the body’s system)
addiction
dependence; Psychological - crave the feeling / effect of the drug; Physiological - without the drug → physical withdrawals
withdrawal
Pain or discomfort from the lack of the chemical
executive functioning
the mental processes that enable us to plan, focus attention, remember instructions, and juggle multiple tasks successfully
prefrontal cortex
large portion of the frontal lobe; deals with personality, abstract thought, emotion, behavior, broca’s area