Cell signalling basics

Communication steps

Messenger molecule - production - packaging- release- termination

What is included in local communication and give definition

Gap junction: form direct cytoplasmic connections

Contact-dependent signals: share a part of the membrane

Define autocrine

communicate with the same cell

define paracrine

communicate with nearby cells

What is long ditsnace communication

• may be electrical signals and neurons

• or circulatory system

• slower and requires stabilizing for the endocrine

define neurohormones

Chemicals are released by neurons into the blood for action at distant targets

What is signal transduction

a process which converts one form of a signal into a different form

Signal transduction pathway

1. External signal

2. Receptor

3. transducer

4. amplifier

5. response

6. termination

   

What are the types of receptors

1. intercellular receptors

2. cell membrane receptors

How do intercellular signal receptors work

• lipophilic signal molecule diffuse through the membrane

• they connect to receptors in cytosol or nucleus

• slower responses due to changes in gene activity

How do cell membrane receptors work

• Extracellular signal molecule binds to membrane receptor

• rapid response

define stickability

The ability of a molecule to bind to a receptor

Define doability

The ability of a molecule and a receptor structure to do something