Meiosis
A pair of cell divisions that produces gametes (or spores in plants & fungi) in sexually reproducing organisms. A diploid parent produces four haploid daughter cells which are genetically different from each other and the parent.
Meiosis I
– First division of meiosis. It begins with a diploid parent cell and produces two daughter cells that will then progress through meiosis II.
Prophase I
Chromosomal DNA condenses. Homologous chromosomes pair together. Crossing over occurs between homologous pairs
Prometaphase I
Nuclear envelope dissolves
Metaphase I
Chromosomes align at middle
Anaphase I
Homologous chromosomes disconnect. Then homologous chromosomes move to opposite sides
Telophase I
Nuclear envelopes reforms; Chromosomes decondense; Cytokinesis
Meiosis II
Second division of meiosis. The two daughter cells from meiosis I will divide again to form a total of 4 daughter cells
Prophase II
Chromosomal DNA condenses
Prometaphase II
Nuclear envelope dissolves
Metaphase II
Chromosomes align on midline
Anaphase II
Sister chromatids disconnect. Then sister chromatids move to opposite sides
Telophase II
Nuclear envelope reforms; Chromosomes decondense; cytokinesis
Cytokinesis
Separation of a cell and its contents to form to daughter cells. In animals the cell membrane pinches to separate daughter cells. In plants, a cell wall is built between daughter cells. Cytokinesis usually occurs during telophase I and II of meiosis
Sexual reproduction
when a new organism is produced from the fusion of two haploid gametes to form a diploid zygote in the process called fertilization
Gamete
cells that fuse to produce a zygote during sexual reproduction. Many organisms produce male gametes called sperm and female gametes called ova
Sperm (gamete)
male sex cell. Usually small cell optimized for swimming to the egg
Egg or Ovum (plural ova)
Female sex cells. Eggs are usually large cells providing nutrients proteins for the developing organism
Somatic cell
Cells in a body of a multicellular organism that divide through mitosis but do not undergo meosis
Chromosomes
molecules of DNA containing genetic information which are coiled around proteins called histones. In eukaryotes they are linear but in prokaryotes they are circular
Gene
A region of DNA on a chromosome that encodes for a specific protein or RNA
Allele
A specific version of a gene. Different alleles can, but do not always, result in detectable differences in the gene products
Sister chromatid
one of the two replicated DNA molecules in a condensed chromosome at the start of mitosis or meiosis. Sister chromatids are held together by cohesion
Cohesion
A protein complex that holds sister chromatids together from the time DNA replicates until chromatids separate during division
Homologous chromosome pairs
homologous chromosomes contain the same genes in the same genes at the same locations but can have different alleles. They also have the same size, shape, and centromere positions
Synaptonemal complex
A protein complex that attaches the homologous chromosomes together during prophase I of meiosis
Haploid
A cell is said to be haploid when it contains only one chromosome from each homologous pair. Haploid cells have a single allele for each gene. In sexual reproducing organisms, haploid cells are generated from diploid cells by meiosis
Diploid
A cell is said to be diploid when it contains two versions of each chromosome called a homologous pair. Diploid cells have two copies of each gene but they can have different alleles in sexually reproducing organisms, one of the chromosomes in each homologous pair is from the father, the other from the mother
Ploidy
This refers to the number of chromosomes in each homologous set, and is denoted as a multiple of the symbol, n. Haploid (1n), Diploid (2n), Triploid (3n), tetraploid (4n)
Homozygous
homologous chromosomes have the same allele for the gene
heterozygous
homologous chromosomes have different alleles for the gene
Independent assortment
The random inheritance of chromosomes during meiosis I. Each daughter cell randomly and independently receives one of the two homologous chromosomes from each pair. Along with crossing over, independent assortment helps randomize combinations of alleles inherited by gametes
Crossing over (recombination
This is the swapping of alleles between homologous chromosomes during prophase I of meiosis. DNA molecules are cut in corresponding locations of each chromosome, and pieces of it are reattached to the homologous partner. The cuts and reattachment are made at the same location on both homologues, which assures that the number of alleles per chromosome does not change
Genetic linkage
Alleles from nearby genes on the same chromosomes are said to have genetic linkage, because crossing over is less likely to occur between nearby genes than between distant genes. (genes from different chromosomes are never linked)
Trisomy
An aneuploid that occurs when a cell has three homologous copies of a chromosome. Trisomy is different from triploid cells (3n): Triploid cells have 3 of every homologous chromosome whereas trisomic cells have a single extra chromosome
Monosomy
An aneuploid that occurs when a cell has a single chromosome from a homologous pair. Monosomy is different from haploid cells (1n): Haploid cells have one chromosome from every homologous pair whereas monosomic cells are missing a single chromosome
Sex chromosome
chromosomes that are instrumental in sex determination. In humans there are two distinct sex chromosomes, X and Y, that differ in size and gene content. some species do not have sex chromosomes and their sex is not determined genetically
autosomes
chromosomes that do not determine sex
hermaphrodite
organisms in kingdom animalia that possess both male and female sex organs and produce both sperm and eggs
self-fertilization
this occurs when two gametes from the same individual fuse in fertilization
Magnification
the process of enlarging the apparent size of an object
resolution
the ability of a microscope to distinguish detail: the minimum distance at which 2 distinct points of a specimen can still be seen as separate entities
cell cycle
the repeating progression of events for dividing cells. it is comprised of two growth phases (G1 and G2), mitosis (M phase) and DNA replication (S phase)
DNA replication (S phase)
the process of copying DNA molecule within the cell. DNA replicates during S phase of the cell cycle
Interphase
The collective name for the parts of the cell cycle that are the 2 growth phases (G1 and G2) and the DNA replication (S phase). In other words, everything in the cell cycle EXCEPT mitosis (M)
Mitosis (M phase)
The phase of the cell cycle where eukaryotic cells divide into two genetically equivalent daughter cells
Prophase
first stage of mitosis, during which DNA coils to form condensed chromosomes
prometaphase
the second stage of mitosis, during which the nuclear envelope dissolves and the spindle attaches to chromosomes
metaphase
the third stage of mitosis, during which the chromosome (pulled by the spindle) aligns along the middle
anaphase
the fourth stage of mitosis, during which cohesion dissolves, sister chromatids separate, and the spindle begins to pull sister chromatids to opposite poles of the cell
telophase
the fifth and final stage of mitosis, during which the nuclear envelopes reform, chromosomes decondense, and, in most cells, cytokinesis forms the daughter cells
Cytokinesis
separation of a cell and its contents to form two daughter cells. In animals the cell membrane pinches to separate daughter cells. In plants, a cell wall is built between daughter cells. Cytokinesis usually occurs during telophase of mitosis