Synaptic Transmission Steps | Quizlet

An "Order Arrives" at the warehouse.

1. Action potential arrives at the presynaptic terminal.

The manager swipes the special "Calcium Card"

2. Ca²⁺ enters the presynaptic terminal.

The delivery vans (vesicles) drive to the loading dock.

3. Vesicles move to the presynaptic membrane.

The delivery vans "dock" or fuse with the loading bay.

4. Vesicles fuse with the presynaptic membrane.

The packages (neurotransmitters) are released into the street.

5. Neurotransmitter is released into the synaptic cleft.

The packages are carried across the street (cleft).

6. Neurotransmitter crosses the cleft.

The package fits into the specific mailbox/keyhole (receptor).

7. Neurotransmitter binds to receptors on the postsynaptic membrane.

Unlocking the mailbox opens the front door (ion channels).

8. Ion channels open on the postsynaptic membrane.

People rush in, delivering the message inside the house.

9. Postsynaptic signal is generated.

The empty packages are cleared away from the mailbox.

10. Neurotransmitter is removed from the synaptic cleft.