DNA Viruses (2)

Brick-shaped

The virion shape of Poxviridae is best described as:

Complex

The capsid symmetry of Poxviridae is:

Mulberry appearance

The surface of Poxvirus may exhibit which characteristic appearance?

Skin abrasions and contact with infected animals

Poxviruses are typically acquired through:

Epidermal cells

The primary site of Poxvirus replication is:

PCR

The most sensitive and preferred diagnostic method for Poxvirus is:

Brick-shaped virion

Electron microscopy of Poxvirus reveals:

Guarnieri bodies

The inclusion bodies seen in Poxvirus infection are called:

Light microscopy

Which diagnostic method may demonstrate Guarnieri bodies?

Variola virus

The virus responsible for smallpox is:

Eradicated/extinct

Smallpox is currently considered:

More severe form

Variola major is characterized as:

Alastrim

Variola minor is also known as:

Less severe

Variola minor infection is:

Avirulent form of Variola virus

Vaccinia virus is described as:

Vaccine production

Vaccinia virus is primarily used for:

Humans only

Molluscum contagiosum virus infects:

Benign skin infection

Molluscum contagiosum causes:

Dome-shaped papules

The lesions of molluscum contagiosum are described as:

Pimple-like bumps

These lesions resemble:

Skin-to-skin contact

Transmission of molluscum contagiosum occurs via:

Water warts

Molluscum contagiosum is also known as:

Sheep to humans

Orf virus is transmitted from:

Direct contact with infected animals

Transmission of Orf virus occurs through:

Weeping nodules

Orf virus typically causes:

Hands

The lesions of Orf virus are usually located on:

Monkeypox

Mpox was formerly known as:

Primates

Mpox was first described in:

1970

The first human case of Mpox was reported in:

Central and Western Africa

Mpox infection primarily occurs in:

Vesicular and pustular febrile illness

Human Mpox infection presents as:

Smallpox

Mpox disease resembles which infection?

Less severe

Compared to smallpox, Mpox infections are:

Significantly lower

Mortality rate in Mpox compared to smallpox is:

Hepatitis B virus

The only recognized virus under the family Hepadnaviridae is:

Dane particle

The virion of Hepatitis B virus (HBV) is also called:

Liver

HBV primarily infects which organ?

Humans

The only natural source/reservoir of HBV is:

Liver

HBV infection may lead to significant damage in the:

Liver

The latency site of Hepatitis B virus is:

Reverse transcriptase

HBV replication involves which unusual enzyme?

DNA → RNA → DNA

The replication process of HBV follows which sequence?

Parenteral (IV)

The major mode of transmission (MOT) of HBV is:

Perinatal and sexual contact

HBV may also be transmitted through:

Retains infectivity in dried blood for several days

HBV is considered heat-stable because it:

HDV

HBV co-infection may occur with which virus?

Deficient RNA virus

Hepatitis D virus (HDV) is classified as:

HBV

HDV requires which virus for replication?

In vitro systems

HBV is described as not cultivable in:

HBsAg

The most reliable marker for identifying HBV infection is: