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Silent
Nucleotide substitution doesn’t change amino acid
Missense
Nucleotide substitution changes the amino acid
Nonsense
Nucleotide substitution creates a stop codon
Frameshift
Insertion or deletion that changes the reading frame of translation
Genetic Variation
Raw material for evolutionary change
Genetic Mutation
Permanent change in base sequences
Point Mutation
Single nucleotide substitution leads to a change in a specific codon
Mutagen Examples
x-rays, UV radiation, exposure to chemicals, and viruses