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Meiosis
Creates haploid daughter cells
Sexual reproduction
Alternation of haploid gametes with diploid zygotes
Germ-line cells
in multicellular organism’s, cells whose descendants may eventually form gametes are
Synapsis
Early in meiosis, chromosomes pair up in a process called
synaptonemal complex
The chromosomes are held together by a complex of proteins called the
Crossing over, Genetic recombination
During synapsis, homologous sections of DNA may exchange places, This is called_____and result in____
Independent assortment
the orientation of homologous chromosomes
Dominant traits
Are always expressed when inherited
An individual homozygous dominant for trait A (genotype AA) mates with one homozygous recessive for the same trait (genotype aa) what genotype and phenotype will their offspring have?
They will all be heterozygous with a dominant phenotype
The Principle of Segregation says that
Gametes inherit only a single allele of each gene
According to the principle of independent assortment
A gamete may inherit any combination of maternal and paternal alleles
Continuous traits
Are likely to be polygenic
You mate two plants together and plant some of the resulting seeds in a greenhouse and some in an outdoor garden. Those planted in the garden are shorter on average than those in the greenhouse. What is the likely explanation?
Phenotypic plasticity
Multiple alleles of a gene code for alternate functional versions of an enzyme. What pattern of inheritance would be most likely for these traits?
Codominace
You examine a mammal where a single gene H codes for hair patterns. HH individuals have long hair, hh individuals are bald, and Hh individuals have short hair. What pattern of inheritance have you observed?
Incomplete dominance
The chromosomal theory of inheritance states that
The inheritance of traits is mediated by the inheritance of chromosomes
Autosomes are
Chromosomes not involved in sex determination
Sex linked traits
May be expressed more often in certain sexes than others
Where would you most likely encounter dosage compensation?
In a homozygous individual of a species with an XY sex determination system
Recessive traits
May skip generations in pedigree analysis
What is the relationship between dominance and sex-linkage of a trait
There is no relationship dominance is determined by whether a gene codes for a functional protein and sex-linkage is whether a gene occurs on a sex chromosome
The complementarity of the two strands of a DNA molecule mean that
You can determine the nucleotide sequence on one strand if you know the sequence on the other
During DNA replication
Each strand of the original molecule is used as a template for a new strand
During DNA replication, primers
Are made of RNA by RNA polymerase
Where would you find Okazaki fragments?
The lagging strand of a replication fork
What is the difference between the leading and lagging strand of a replication fork?
The leading strand can be replicated in one continuous segment, while the lagging strand is copied in multiple segments
What is the difference between DNA polymerase 1 and DNA polymerase 3
DNA polymerase 1 replaces RNA primers with DNA, while DNA polymerase 3 synthesizes new DNA strands
What does telomerase do?
Extends telomeres
Mutagens
Cause changes in DNA structure or sequence
In DNA transcription
A segment of DNA is copied into a strand of mRNA
The genetic code
May contain multiple codons that code for more than one amino acid
Silent mutations
Are possible because the genetic code is degenerate
Transfer RNA (tRNAs)
Form the link between nucleotide codons and amino acids
Mutations
Is/are the ultimate source of all genetic variation
All of the following are common modifications of eukaryotes RNA transcripts expect
Transcription by DNA polymerase instead of RNA polymerase
Promoter sequences
Serve as binding sites for RNA polymerase
Eukaryotes may produce multiple proteins products from a single gene through the use of
Alternate splicing of exons
The genetic code includes two types of punctuation codons called____codons and ____ codons
Start, stop