Group I Introns, Group II Introns, and snRNA Splicing
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4 Terms
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How does splicing occur in group I introns?
Group I introns use a free guanosine nucleotide as a cofactor to initiate self-splicing without proteins.
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How does splicing occur in group II introns?
Group II introns self-splice using an adenosine within the intron to form a lariat intermediate.
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How does snRNA splicing occur?
Spliceosomal snRNAs form a complex with proteins to catalyze intron removal and exon ligation in pre-mRNA.
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What is the key difference among them?
Group I and II introns are self-splicing, while snRNA splicing requires the spliceosome. Group II splicing resembles spliceosomal mechanisms evolutionarily.
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