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Key Vocabulary and Functions. Make sure to study the fetal pig
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Key functions of the cardiovascular system
transportation (blood gases, nutrients, hormones, wastes), regulation (homeostasis of body temperature, electrolytes, pH), coagulation (blood clotting following an injury), and immunity (white blood cells)
Components of blood
plasma, leukocytes, erythrocytes, platelets
Plasma
a mixture of water, electrolytes, and proteins that help in transporting lipids, forming antibodies, and blood clotting
Leukocytes
white blood cells that fight disease and infection
Erythrocytes
Red blood cells that transport oxygen
Platelets
red blood cells that help from blood clots
Properties of erythrocytes (red blood cells)
biconcave disk shape, no nucleus, no mitochondria, able to deform to fit through blood vessels
hemoglobin
protein that can bind to oxygen and carbon dioxide
What is the role of kidneys in monitoring low oxygen levels?
The kidneys act as crucial oxygen sensors that monitor low oxygen level by producing the hormone erythropoietin (EPO) in response. When renal oxygen levels fall, EPO is released to stimulate the bone marrow to produce more oxygen-carrying red blood cells, maintaining systemic homeostasis.
Arteries
transports blood (AWAY) from the heart and blood is typically oxygenated in the systemic circuit
Veins
transports blood towards the heart and carries CO2 in the systemic circuit (deoxygenated)
Capillaries
connect arteries to veins in the systemic circuit; where oxygen is released and CO2 is absorbed
Difference between arteries, veins, and capillaries
Arteries: thicker wall of smooth muscle to regulate blood flow
Veins: thinner walls, larger lumens, and valves to prevent backflow of blood
Capillaries: only have a single layer of squamous cells to allow diffusion of oxygen and CO2
Key exception of arteries
Pulmonary arteries carry deoxygenated blood from the heart to the lungs
Key exception of veins
Pulmonary veins carry oxygenated blood from the lungs to the heart
antigens
particles on the surface of molecules or cells that identify or unify a group
antibodies
immunity defense mechanism that targets specific antigens and triggers the immune system to destroy
Rh-factor
the ± symbol (also known as the D-antigen); determines if the blood has the factor and is positive (+) or does not have the factor and is negative (-)
The universal donor
O-
The universal reciever
AB+
What can negative blood do that positive blood can not?
Negative blood can safely donate to positives but not the other way around
Agglutination tests
blood test that intentionally exposes blood to antibodies to see if they react; clumping blood is a positive result
What is the role of muscle contraction in blood flow?
Contracting muscles compress veins and forces blood toward the heart assisted by one-way valve
Systolic blood pressure
the maximum force following ventricular contraction; top number of blood pressure
Diastolic blood pressure
the minimum force during ventricular refill
Blood pressure
the force placed on arterial walls as the heart pumps
Hypertension
chronically high blood pressure
Hypotension
blood pressure lower than 90/60
Aneurysms
weakening of artery walls, causing them to bulge outwards
Stroke
blood flow to the brain is interrupted caused by ruptures or blood clots in arteries
Spleen
important organ for maintaining blood supply
Stores blood
Produces leukocytes and antibodies to remove bacteria and viruses.
Filters out deformed and aging erythrocytes from circulation.
Iron deficiency anemia
a common blood disorder where the body lacks sufficient iron to produce adequate hemoglobin, the protein in red blood cells that transports oxygen
Sickle cell anemia
a severe, inherited blood disorder where red blood cells become rigid, crescent-shaped, and sticky, hindering oxygen flow
Polysythemia
a blood disorder characterized by an abnormal increase in red blood cells (RBCs), leading to thicker blood, reduced blood flow, and potentially serious clots
Leukemia
a cancer of the blood-forming tissues, including bone marrow, causing rapid, uncontrolled production of abnormal white blood cells that cannot fight infection
Sequence of how blood flows through the heart
1) Superior//interior Vena Cava
2) Right atrium
3)Tricuspid valve
4) Right Ventricle
5) Pulmonary valve
6) Pulmonary Artery
7) Lungs
8) Pulmonary Veins
9) Left Atrium
10) Bicuspid Valve (mitral)
11) Left Ventricle
12) Aorta
13) Body
Lungs
organ responsible for gas exchange—oxygenating blood and removing waste carbon dioxide
Four sets of muscles assist in breathing
The intercostal muscles expand and contract the ribcage.
The pectoralis minor and serratus anterior help raise the rib cage during breathing.
The diaphragm moves up and down.
How many lobes of the lungs?
Right Lung (3 lobes): Upper lobe, middle lobe, lower lobe.
Left Lung (2 lobes): Upper lobe, lower lobe.
asthma
narrowing of the airway accompanied by excess mucus
Inhalation
the active biological process of drawing air, oxygen, or other substances into the lungs; it involves the contraction of the diaphragm and intercostal muscles, which expands the thoracic cavity
Exhalation
the biological process of expelling air from the lungs, serving as the passive phase of breathing where the diaphragm and external intercoastal muscles relax