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Biomedical engineering
The application of engineering principles to biological systems to improve healthcare through devices, technologies, and therapies.
What makes biomedical engineering unique
It directly impacts human health, involves biological complexity, and is highly regulated.
Design in biomedical engineering
An iterative process that transforms a problem into a safe and effective solution that meets user needs.
User need
A non-technical description of what the user requires from a device.
Design input
A measurable and testable requirement derived from user needs.
Verification
Confirming that design outputs meet design inputs.
Validation
Confirming that the final device meets user needs in real-world use.
Why iteration is important in BME
Biological systems are unpredictable and require refinement to ensure safety and usability.
IRB oversight required
When research involves human subjects and potential risk.
Four major classes of biomolecules
Carbohydrates, lipids, proteins, and nucleic acids.
Polymer
A large molecule made of repeating monomer units.
Bond that forms polymers
Covalent bonds.
Why water is polar
Oxygen pulls electrons more strongly than hydrogen, creating partial charges.
Why water is essential for life
It dissolves polar molecules, supports chemical reactions, stabilizes temperature, and enables molecular interactions.
Hydrophobic interactions
The tendency of nonpolar molecules to cluster together in water.
Difference between DNA and RNA
DNA stores genetic information while RNA carries instructions for protein synthesis.
DNA and RNA base pairing
DNA uses A–T and G–C; RNA uses A–U and G–C.
Transcription
The process of making RNA from DNA.
Translation
The process of making a protein from RNA.
Codon
A three-nucleotide sequence that codes for an amino acid.
Why protein structure matters
The shape of a protein determines its function and interactions.
Neuroplasticity
The brain’s ability to change structure and function in response to experience or injury.
Conditions that promote neuroplasticity
Repetition, challenge, feedback, attention, and engagement.