Ovaries and Follicles

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13 Terms

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What are ovaries?

Paired glands that provide for the development of oocytes and production of hormones

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What is ovulation?

The release of mature oocytes

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Where are the ovaries located?

To its respective right or left kidney and is suspended form the dorsal wall of abdomen

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Parts of the Ovary

  • What covers the ovary 

  • What is the periphery of ovary called 

    • Function 

  • What is the middle of ovary called 

    • Function

What covers the ovary: Tunica albuginea

What is the periphery of ovary called: Cortex (functional part

  • Function: Contains large mass of follicles in various stages of development

What is the middle of ovary called: Medulla (supportive part)

  • Function: Contains loose connective tissue, blood vessels, lymphatics and nerves

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<p>Picture of&nbsp;</p>

Picture of 

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What are the 3 types of follicles in oocyte?

  • Primordial follicle #ffb3c6

  • Growing follicle #ff8fab

  • Graafian follicle #fb6f92

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Primordial Follicle #ffb3c6

  • What does it contain 

  • Where do the oocyte in primordial follicle come from?

What does it contain: A single oocyte surrounded by.a single layer of granulosa cells

Where do the oocyte in primordial follicle come from: 

  • Derived from mitosis of oogonia in the embryonic genital ridge 

  • Which then migrates to the ovary 

<p><strong><u>What does it contain:</u>&nbsp;</strong>A<strong> </strong><span style="color: rgb(255, 179, 198);"><strong>single oocyte</strong></span> surrounded by.a<strong> </strong><span style="color: rgb(255, 179, 198);"><strong>single layer</strong></span> of<strong> </strong><span style="color: rgb(255, 179, 198);"><strong>granulosa cells</strong></span></p><p><strong><u>Where do the oocyte in primordial follicle come from:</u>&nbsp;</strong></p><ul><li><p>Derived from<strong> </strong><span style="color: rgb(255, 179, 198);"><strong>mitosis</strong></span> of<strong> </strong><span style="color: rgb(255, 179, 198);"><strong>oogonia</strong></span> in the<strong> </strong><span style="color: rgb(255, 179, 198);"><strong>embryonic genital ridge&nbsp;</strong></span></p></li><li><p>Which then<strong> </strong><span style="color: rgb(255, 179, 198);"><strong>migrates</strong></span> to the<strong> </strong><span style="color: rgb(255, 179, 198);"><strong>ovary</strong></span>&nbsp;</p></li></ul><p></p>
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Growing Follicle #ff8fab

  • What 

  • What structures are absent in a growing follicle 

What: A follicle that has begun developing from the primordial stage but not yet formed thecal layer or antrum

Structures absent: Thecal layer or antrum 

<p><strong><u>What:</u> </strong>A follicle that has <span style="color: rgb(255, 143, 171);"><strong>begun developing</strong></span><strong> </strong>from the <span style="color: rgb(255, 143, 171);"><strong>primordial stage</strong></span><strong> </strong>but <span style="color: rgb(255, 143, 171);"><strong>not yet</strong></span> formed<span style="color: rgb(255, 143, 171);"><strong> thecal layer</strong> </span>or<strong> </strong><span style="color: rgb(255, 143, 171);"><strong>antrum</strong></span></p><p><strong><u>Structures absent:</u>&nbsp;</strong><span style="color: rgb(255, 143, 171);"><strong>Thecal layer</strong></span> or<strong> </strong><span style="color: rgb(255, 143, 171);"><strong>antrum</strong></span><strong>&nbsp;</strong></p>
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Graafin Follicle? #fb6f92

  • What

  • What controls the formation of Graafian follicles

  • When does the formation start

What: A mature follicle with a visible antrum and 2 thecal layers

  • Theca interna 

  • Theca extera

What controls the formation of Graafian follicles:

  • Its hormone dependent

Formation starts: At puberty when LH and FSH levels start to rise and fall with each estrous cycle

<p><strong><u>What:</u> </strong>A <span style="color: rgb(251, 111, 146);"><strong><span>mature follicle</span></strong></span><strong> </strong>with a <span style="color: rgb(251, 111, 146);"><strong><span>visible antrum</span></strong></span><strong> </strong>and <span style="color: rgb(251, 111, 146);"><strong><span>2 thecal layers</span></strong></span></p><ul><li><p><span style="color: rgb(251, 111, 146);"><strong><span>Theca interna&nbsp;</span></strong></span></p></li><li><p><span style="color: rgb(251, 111, 146);"><strong><span>Theca extera</span></strong></span></p></li></ul><p><strong><u>What controls the formation of Graafian follicles:</u></strong></p><ul><li><p>Its<span style="color: rgb(251, 111, 146);"> <strong>hormone dependent </strong></span></p></li></ul><p><strong><u>Formation starts:</u> </strong>At <span style="color: rgb(251, 111, 146);"><strong>puberty</strong></span><strong> </strong>when <span style="color: rgb(251, 111, 146);"><strong>LH</strong></span><strong> </strong>and <span style="color: rgb(251, 111, 146);"><strong>FSH</strong></span><strong> </strong>levels start to <span style="color: rgb(251, 111, 146);"><strong>rise</strong></span><strong> </strong>and <span style="color: rgb(251, 111, 146);"><strong>fall</strong></span><strong> </strong>with <span style="color: rgb(251, 111, 146);"><strong>each estrous cycle </strong></span></p>
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Zona pellucida

  • What

  • Its function to fertilisation

What: A glycoprotein layer surrounding the oocyte

Function to fertilisation: Sperm must recoginse, bind and travel through zona pellucida to reach oocyte plasma membrane

<p><strong><u>What:</u> </strong>A <span style="color: red;"><strong>glycoprotein layer </strong></span>surrounding the <span style="color: red;"><strong>oocyte</strong></span></p><p><strong><u>Function to fertilisation:</u> </strong><span style="color: red;"><strong>Sperm</strong></span><strong> </strong>must <span style="color: red;"><strong>recoginse</strong></span><strong>, </strong><span style="color: red;"><strong>bind</strong></span><strong> </strong>and <span style="color: red;"><strong>travel through zona pellucida</strong></span><strong> </strong>to reach <span style="color: red;"><strong>oocyte plasma membrane </strong></span></p>
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What is follicle regression?

  • The periodic process in which immature ovarian follicles degenerate

  • And are re-absorbed during the follicular phase of the menstrual cycle

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What happens to the multiple follicles that mature each month?

  • Only 1 follicle is ovulated 

  • Remaining undergo atresia 

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What happens to the single dominant follicle after ovulation?

It becomes corpus luteum