Feline Anesthesia

Morphine classification and MOA

mu opioid agonist

acts directly on opioid receptors in central nervous system

Morphine use

sedation, analgesia, decrease MAC

about 4 hour duration

Morphine side effects

emesis, respiratory depression, bradycardia

Dexmedetomidine classification and MOA

alpha 2 agonist

decreases sympathetic tone

Dexmedetomidine use

sedation, analgesia, muscle relaxation, decrease MAC

1-1.5 hour duration

Dexmedetomidine side effects

vasoconstriction, reflex bradycardia, decrease in cardiac output, emesis

Propofol classification and MOA

GABA agonist

works on central nervous system

Propofol use

induction agent - unconsciousness, muscle relaxation, facilitation in intubation

10-15 minute duration

Propofol side effeccts

respiratory depression → apnea

cardiovascular depression → vasodilation, decreased myocardial contractility

Cefazolin

perioperative antibiotic

side effect - vasodilation

Glycopyrrolate classification and MOA

anticholinergic

inhibits parasympathetic nervous system

Glycopyrrolate use indication

bradycardia w/o concurrent hypotension

45-60min duration

Glycopyrrolate side effects

tachycardia

decreased mucous secretion

Atropine

anticholinergic that acts on muscarinic receptors

Epinephrine

sympathomimetic

alpha and beta adrenergic receptor

Lidocaine

sodium channel blocker

local block

Simbadol

partial mu agonist

prolonged analgesia

Ketamine

NMDA receptor

anti-nociceptive, dissociative anesthesia

Bupivacaine

sodium channel blocker

local block that lasts longer than lidocaine