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Neuron
The main communication cell of the nervous system.
Dendrites
Receive signals (input) for the neuron.
Cell body (soma)
Processes information within the neuron.
Axon
Sends electrical signals away from the soma.
Axon terminals (boutons)
Release neurotransmitters to communicate with the next neuron.
Action potential
An all-or-none electrical signal that travels down the axon.
Graded potential
A small change in membrane potential that can build up.
Depolarization
Process where sodium (Na⁺) channels open and the inside of the cell becomes more positive.
Repolarization
Process where potassium (K⁺) leaves the cell returning it to a negative state.
Sodium-potassium pump
Restores resting potential by moving 3 Na⁺ out and 2 K⁺ in.
Synapse
Junction between two neurons where neurotransmitters are exchanged.
Excitatory neurotransmitter
Increases the likelihood of the next neuron firing (e.g., glutamate).
Inhibitory neurotransmitter
Decreases the likelihood of the next neuron firing (e.g., GABA).
Acetylcholine (ACh)
Neurotransmitter involved in motor control and muscle contraction.
Dopamine
Neurotransmitter associated with reward, movement, and motivation.
Serotonin
Neurotransmitter involved in mood and sleep regulation.
Norepinephrine
Neurotransmitter related to alertness and stress.
Multipolar neurons
Neurons with many dendrites and one axon; most common type.
Bipolar neurons
Neurons with one dendrite and one axon; found in retina and olfactory system.
Unipolar neurons
Neurons with a single projection; primarily sensory neurons.
First-order neuron
Neurons that detect stimulus in skin or sense organs.
Second-order neuron
Located in spinal cord or brainstem; sends information to the thalamus.
Third-order neuron
Located in the thalamus; sends information to the cortex.
Dorsal column–medial lemniscus
Sensory tract responsible for fine touch, vibration, and proprioception.
Spinothalamic tract
Sensory tract that transmits pain and temperature information.
Trigeminothalamic tract
Sensory tract that carries information from the face to the thalamus.
Optic chiasm
Crossing point of nasal retinal fibers that allows both eyes to share vision.
Tonotopic organization
Auditory system arrangement where specific frequency sounds are represented in specific areas.
Perilymph
Fluid in the scala vestibuli and scala tympani of the cochlea.
Endolymph
Fluid in the scala media of the cochlea.
Motor unit
A motor neuron and all the muscle fibers it controls.
Neuromuscular junction
The site where a motor neuron communicates with a muscle fiber.
Upper Motor Neuron (UMN)
Neurons that project from the cortex to the brainstem or spinal cord.
Lower Motor Neuron (LMN)
Neurons that project from the brainstem or spinal cord to the muscle.
Pyramidal System
System responsible for voluntary movement controlled directly from the cortex to muscles.
Corticospinal tract
Pathway that controls limbs and body from the cortex to spinal cord.
Corticobulbar tract
Pathway that controls face and speech muscles from the cortex to cranial nerves.
Extrapyramidal System
System involved in automatic control of movement, posture, and reflexes.
Cerebellum
Brain structure responsible for coordinating timing, precision, and balance of movement.
Projection neurons
Neurons that send signals over long distances.
Local neurons
Neurons that communicate within a specific region.
Afferent
Refers to sensory neurons that carry information to the central nervous system.
Efferent
Refers to motor neurons that carry information away from the central nervous system.
LMN lesion
Causes weakness, atrophy, and fasciculations in affected muscles.
UMN lesion
Leads to spasticity and hyperreflexia in affected areas.