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In the eye, rods mediate __________, and cones mediate __________.
a. both mediate color only
b. both mediate movement only
c. light and movement, color vision
d. color vision, light and movement
e. both mediate color vision, light, and movement to the same extent
c
Low frequency sounds are processed in which part of the cochlea?
a. base
b. apex
c. mid-portion
d. all throughout the cochlea
e. none of the above
b
While going from the retina to the cortex, visual pathways innervate what part of the thalamus?
a. lateral geniculate
b. medial geniculate
c. superior colliculus
d. inferior colliculus
e. none of the above
a
What does the term "tonotopic representation" mean?
A) Only the auditory cortex has a systematic arrangment of neurons according to the frequency of the sound
B) The systematic arrangement of cells does not begin until the cochlear nucleus
C) Systematic arrangement of frequency extends all the way from the cochlea to the auditory cortex
D) Every location along the basilar membrane (within the cochlea) represents every frequency within the limits of human hearing (20-20kHz)
C
Why is neural activity in the left and right sides of the brainstem combined? (That is, why are there connections between nuclei on the left and right sides of the brainstem?).
A) The combination allows a sharper definition of which frequencies have entered the auditory system
B) The combination is importany for analysis of speech
C) The combination is simply because similar structures (such as the superior olivary nuclei) on either side of the brainstem tend to be connected
D) The combination allows cues such as timing and intensity differences entering the two ears to be used for localizing the source of sound in the environment
D
T or F: The auditory nerve and the primary auditory cortex are tonotopically organized.
T
T or F: During the endocochlear potential, depolarization occurs because of an outflow of Ca++ and K+ from the hair cell.
F
T or F: In the ear, the stapes makes contact with the round window.
F
T or F: Visual information about where an object is in space and in relation to your body is processed in the dorsal stream association area:
T
The Organ of Corti is located in the...
a. Scala Vestibuli
b. Scala Tympani
c. Scala Media
d. Cochlear Nucleus
e. None of the above
c
Where does hearing become binaural, in terms of the pathways from the cochlea to the cortex?
a. Cochlear Nucleus
b. Auditory Nerve
c. Superior Olive
d. Superior Colliculus
e. Thalamus
c
The cues required to localize sounds from either the left or right are processed in what nucleus of the auditory pathway?
a. Cochlear Nucleus
b. Superior Colliculus
c. Auditory Nerve
d. Medial Geniculate
e. Superior Olive
e
T/F: The auditory nerve and the primary auditory cortex are tonotopically organized.
True
T/F: During the endocochlear potential, depolarization occurs because of an outflow of Ca++ & K+ from the hair cell.
False
T/F: In the ear, the stapes makes contact with the round window.
False
T/F: Visual information about where an object is in space and in relation to your body is processed in the dorsal stream association area.
True
A person presents with flaccid weakness, decreased stretch reflexes and muscle fasciculation. Which of these would you expect to be damaged?
a. Sensory neurons
b. Basal ganglia
c. Lower motor neuron
d. Cerebellum
e. Upper motor neuron
c
This mediates internally generated movements:
a. Premotor area
b. Sensory area
c. Supplementary motor area
d. Primary motor area
e. Posterior parietal area
c
The cells that comprise the corticobulbar tract have their nuclei in:
a. The post-central gyrus
b. Ventrolateral thalamus (VL)
c. The caudate nucleus
d. The thalamus
e. The cortex
e
Which of these can exert an effect on a lower motor neuron?
a. Cortical cell
b. Fibers in the corona radiata
c. Peripheral sensory fiber
d. All of these can affect a lower motor neuron
e. fibers from sensory nuclei
d
This pathway influences background muscle activity & posture:
a. Vestigial cerebellar
b. Pontocerebellar
c. Vestibulocerebellar
d. Spinocerebellar
e. Cerebrocerebellar
d
The unit responsible for the contraction of a muscle is called the:
a. Actin
b. Myosin
c. Sarcomere
d. T-tubule
e. None of the above
c
T/F: A lesion to the right basal ganglia causes deficits in the right side of the body.
False
T/F: A lesion to the left cerebellum causes deficits to the left side of the body.
True
T/F: Swimming, chewing & swallowing are all examples of reflexive motor behaviors.
False
A child presents to the neurologist with a lateral strabismus of the left eye. She likely has an issue with the:
a. Right Cranial Nerve III
b. Left Cranial Nerve III
c. Right Cranial Nerve VI
d. Left Cranial Nerve VI
e. None of the above.
b
If you have a lesion in the left cerebral cortex motor areas for the face:
a. Drooping & weakness of the entire left side of the face
b. Drooping and weakness of the lower left side of the face
c. Drooping and weakness of the entire right side of the face.
d. Drooping and weakness of the lower right side of the face
e. None of the above
d
This motor only cranial nerve controls the tongue:
a. Trigeminal
b. Facial
c. Glossopharyngeal
d. Vagus
e. Hypoglossal
e
Which of these cranial nerves mediate a specialized sensory function?
a. Optic
b. Trochlear
c. Abducens
d. Oculomotor
e. Hypoglossal
a
A lesion to cranial nerve VIII would cause:
a. Visual deficits
b. Hearing deficits
c. Taste deficits
d. Tongue deficits
e. Olfactory deficits
b
Which of these cranial nerves controls vocal production?
a. VII
b. IX
c. X
d. XII
e. None of these
c
T/F: A lesion in the rostral spinal cord/caudal medulla can cause pain & temperature issues in the face.
True
T/F: During the endocochlear potential, depolarization occurs because of an influx of Ca++ and K+ in the hair cell.
True
In the eye, cones mediate:
a. Color vision
b. Light & movement
c. Light, movement, & color vision
a
High frequency sounds are processed in which part of the cochlea?
a. Base
b. Apex
c. Mid-portion
d. All throughout the cochlea
e. None of the above
a
T/F: The right side of the brain perceives the right side of the visual field.
false
A child presents to the neurologist with a lateral strabismus of the left eye. She likely has an issue with:
a. Right CNIII
b. Left CNIII
c. Right CNVI
d. Left CNVI
e. None of the above
b
This mediates goal directed movements:
a. Primary motor area
b. Supplementary motor area
c. Premotor area
d. Sensory area
e. Posterior parietal area
c
T/F: A lesion to the right cerebellum causes deficits in the left side of the body.
false
A person has trouble with voice & swallowing. Which cranial nerve do you suspect is impaired?
a. Trigeminal
b. Facial
c. Glossopharyngeal
d. Vagus
e. Hypoglossal
d
A person presents weakness, spasticity, and hyperactive reflexes. Which of these would you expect to be damaged?
a. basal ganglia
b. cerebellum
c. sensory neurons
d. upper motorneuron
e. lower motorneuron
d
The major input to the basal ganglia from the cortex is:
a. Globus pallidus internal segment
b. Globus pallid us external segment
c. Striatum
d. Substantia nigra
e. Nucleus accumbens
c
T/F: The pyramidal system sets background muscle activity on which skilled movements are performed.
false
This part of the sensorimotor system receives a copy of the motor plan and adjusts movements based on feedback from ongoing movement:
a. Thalamus
b. Premotor area
c. Basal ganglia
d. Cerebellum
e. Primary motor area
d
A person has trouble chewing and issues with pain/temperature to the face. Which cranial nerve do you suspect is impaired?
a. Trigeminal
b. Facial
c. Glossopharyngeal
d. Vagus
e. Hypoglossal
a
This part of the limbic system regulates memory:
a. Hippocampus
b. Amygdala
c. Septum Pallucidum
d. Hypothalamus
e. Thalamus
a
photons
light energy
the lends and cornea ________ the electromagnetic energy (photons)
refract (bend)
what converts electromagnetic energy to
retina (photoreceptors)
how do we see
The lens and cornea of the eye refract (bend) the electromagnetic energy (photons)
Electromagnetic energy is converted to nerve impulses by the retina (photoreceptors)
Transmission of the impulses from photoreceptors from retina to cortex (occipital cortex)
Perception of visual images is further processed by association areas
the eyeball is divided into the _______________ anterior and the ___________ ________________ posterior cavity
small
large round
anterior cavity
iris, cornea, lens, aqueous fluid similar to CSF
2 chambers: anterior and posterior
posterior cavity
area between lens and retina
filled with vitreous humor
vitreous humor
jelly-like substance that maintains normal intro-ocular pressure which prevents the eye from collapsing
formed early in life and is never replaced
pathways from the retina to the cortex
Light rays entering the eye are bent by the curvature of the cornea and accommodation of the lens and converge on rods and cones in the retina
The rods populate the peripheral regions of the retina and are sensitive to light and movement
The cones are mostly around the central retinal region where visual acuity is the highest
The photoreceptor cells convert light energy (photons) into nerve potentials that travel through the axons
cones
mediate color vision, which results from differential sensitivity of light wavelengths: red, green and blue
rods
night/low light vision
pathway from eye to cortex
The axons form the optic nerve cross at the optic chiasm and become the optic tract
The optic tract travels posteriorly and terminates in the lateral geniculate body of the thalamus
The geniculate projections called optic radiations travel through the brain to the occipital lobe
The visual cortex in the upper and lower banks of the calcarine fissure receives projections from both eyes
how light gets to the brain
begins with the cornea
iris
pupil
lens
retina
optic nerve
primary visual cortex
cornea
Clear, protective film covering your pupil
Keeps in the vitreous humor and slightly bends the light to direct it into your pupil
iris
Controls amount of light that passes through your pupil
pupil
Hole on surface of iris that light passes through
lens
Focuses light onto the retina
retina
3 layers
photoreceptor layer
bipolar cells
ganglion cells
photoreceptor layer
Signals colors
Gets color information from rods and cones
React to the absence of light
-Darker it is the more glutamate they release
bipolar cells
Transmits signals from the photoreceptors to the ganglion cells
ganglion cells
In the retina, the specialized neurons that connect to the bipolar cells; the bundled axons of the ganglion cells form the optic nerve.
**this blocks part of the retina and this creates a "blind-spot"**
optic nerve
passes through the "cerebral penduncle" to be interpreted into color, images, intensity and brightness
primary visual cortex
where all the visual information ends up
visual field
focused by the eye onto the retinal field
reversed
monocular vision
A portion of your visual field is only seen by one eye
binocular vision
The portions of your visual field that can be seen by both eyes
where do light rays merge into one object in the brain?
cortex
saccades
quick eye movements
parallel processing
capability to process visual components simultaneously
association processing
dorsal stream (where)
central stream (what)
dorsal stream (where)
Integrated motion, temporal and spatial
central stream (what)
Complex and cognitive aspects
Recognizing objects, faces, visual memory, reading
outer ear parts
pinna
external auditory meatus (ear canal)
tympanic membrane
middle ear parts
ossicles (malleus, incus, stapes)
inner ear parts
semicircular canals
cochlea
nerve to brain
cochlea
fluid filled chamber that is tonotopically organized
tonotopic organization
Different frequencies are represent in different areas of the cochlea
Hair length determines what tune it can/can't pick up
higher frequency
hair shorter near the base
List in order the structures that sound acts on, from external ear to inner ear.
External ear:
Gathers sound energy and focus it on the tympanic membrane (eardrum)
It amplifies sound to 2.5 kHz
Middle ear:
Vibrations vibrate the ossicles
The stapes vibrate the oval window which transmits vibrational energy to the fluids of the cochlea
Inner ear:
Converts energy to nerve impulses to be sent and interpreted by the brain
This is done by the cochlea
lower frequency
hair longer near the apex
what three structures make up to organ of corti?
sensory cells
supporting cells
auditory nerve fibers
sensory cells
1 row IHC
3 rows OHC
(receive efferent points from the brain)
stereocilia (stiff point at the tip of the OHC)
tip links (at tip of sterocilia)
What is the function of stereocilia?
height increases as they are arranged left to right
extend into indentations into tectorial membrane
based on the vibrations in the fluid of the cochlea they bend one way or another shifting and moving the tectorial membrane
depending on the direction of the bend the ion channels will open or close which increases/decreases the firing rate of the auditory nerve fibers
How do the membranes and hair cells work to convert sounds into electrical activity?
tip links translate hair bundle movemnt into a receptor potential
when hair bundles are shifted to the right ion channels open which causes an influx of potassium ions and depolarization of the HC which would lead to an influx in Ca2+ ions from calcium gated channel to open at the base of the hC, this triggers NTs to go into the synapse from the base of the HC, the NTs stimulate the afferent nerve fibers which form part of the auditory nerve and the signal is sent to the brain
what is the resting membrane potential of the HC?
150mV
what ions flow to depolarize the membrane?
potassium
where is the auditory cortex found?
the posterior superior temporal gyrus
BA: 41, 42, 22
does the primary auditory cortex have tonotopic organization?
yes, lower frequency sounds are anterior and higher frequency sounds are posterior
binaural hearing
hearing with two ears
ITD
IID
Interaural Time Delay (ITD)
there is a time difference in hearing with two ears, teh ear closer receives auditory stimuli sooner than ear further
the time difference helps with sound localization
Interaural Intensity Difference (IID)
due to dampening (caused by our own heads) there is an intensity difference in one ear compared to the other depending on where exactly the sound stimuli is coming from
makes it easier to locate high frequency sounds compared to low frequency sounds
pathway of electrical auditory stimuli in the brain
spiral ganglia
cochlear nuclei
superior olivary complex
lateral lemniscus
inferior colliculus
thalamus
medial geniculate body
auditory cortex
where in the brain is binaural hearing from both ears shared?
superior olivary complex
Automatic brainstem response testing (ABR testing)
measures the different "stops" the electrical stimuli takes to the brain
peaks show each stop
can be done with otoacoustic emissions test
used to refer a patient for further auditory testing