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What is hypovolaemic shock?
Low volume of blood
Reduced by 15-20%
What are three causes of hypovolemic shock?
Haemorrhage
Vomiting and diarrhoea
Severe burns
What is the most common cause of cardiogenic shock?
Myocardial infarction
What are the two effects of neurogenic shock on the cardiovascular system?
Vasodilation
Bradycardia
What is bradycardia?
Slow heart beat
What is the function of myocardial cells?
Generates electrical impulses for heart contraction
What are the five structures of the heart involved in cardiac conduction?
Sinoatrial node
Atrioventricular node
Atrioventricular bundle
Left and right bundle branches
Purkinje fibres
What is the source of cardiac contraction?
sinoatrial node
What causes the sinoatrial node to be self stimulating?
Electrically unstable causing it to depolarise
What is repolarisation?
Period of recovery of the Sinoatrial node
What is the function of the atrioventricular node?
Transmits signals from atria to ventricles
What is the function of the atrioventricular node delay?
Ensure atria are fully empty and ventricles start to fill
What is the atrioventricular bundle?
Mass of specialised conducting fibres dividing into left and right branches
How do electrical impulses through the ventricles?
Left and right AV bundles branch into Purkinje fibres directly supplying myocardial cells
What is cardiac diastole?
Atria fill with blood from superior vena cava and pulmonary veins
What is atrial systole?
Blood pressure forces AV valves open causes atrioventricular valves to open
Sinoatrial node depolarises
What is ventricular systole?
AV node carries impulses causing ventricles to contract
Blood pressure increases in ventricles forcing valves open and emptying blood
What does ECG stand for?
Electrocardiography
What does the ECG measure?
Electrical activity of the heart caused by polarisation
What are the five waves of a normal ECG trace?
P, Q, R, S, T
What does the p-wave represent?
Atrial depolarisation
What does the pr interval represent?
Atrioventricular node delay
What does the qrs complex represent?
Ventricular depolarisation causing ventricular contraction
What does the st segment represent?
Early ventricular repolarisation
What abnormalities can be detected in the st segment?
Ischemia
Infarction
What does the t wave represent?
Ventricular repolarisation
What does the qt interval represent?
Total ventricular activity
What could qt interval elongation indicate?
Increased risk of arrhythmias
What is ECG paper output speed?
Rate at which the machine produces a trace
How are blood pressure readings expressed?
Systolic pressure/diastolic pressure
What is the normal blood pressure reading?
120/80
Why are systolic and diastolic readings used?
Shows the highest rise and lowest point in arterial pressure
What is pulse pressure?
The difference between systolic and diastolic pressure
What are the three factors determining resistance to flow of fluids in vessels?
Diameter
Length
Viscosity of fluid
What is the main factor controlling blood flow?
Diameter of resistance vessels controlled by smooth muscle in tunica media and sympathetic nerves
What are the two factors determining blood pressure?
Cardiac output x peripheral resistance
How is cardiac output determined?
Stroke volume x heart rate
What is stroke volume?
Amount of blood ejected from ventricles with each beat
What is heart rate?
Rate of cardiac cycle measured in beats per minute
What is peripheral resistance?
Blood pumped into closed circulatory system against blood pressure already there
What is auto regulation?
Ability of an organ to control its own blood flow through local vasolidation or vasoconstriction
What three organs have higher blood flow?
Brain
Kidney
Liver
What are the four mechanisms causing local vasodilation?
Increased metabolic waste production
Increased tissue temperature
Hypoxia
Local vasodilator chemical release
What are the two methods of blood pressure control?
Short term
Long term
What is the cardiovascular centre?
Collection of interconnected neurons responsible for cardiac output and blood pressure
What are three sources of impulses to the cvc?
Baroreceptor and chemoreceptors
Higher centres in the brain
What are baroreceptor?
Receptors in sinuses which sense stretch of blood vessels
What are the two ways the CVC lowers blood pressure?
Increases parasympathetic activity
Reduces sympathetic tone, causing vasodilation
What are the two main systems of long term blood pressure regulation?
Renin Angiostensin Aldosterone system and antiduretic hormone to increase water absorption