Antipsychotics: Interactions

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4 Terms

1
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What can happen when you mix antihypertensives or CNS depressants with phenothiazines (haloperidol)

SEVERE HYPOTENSION

2
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What can happen when you mix anticoagulants with phenothiazines haloperidol)

less effective anticoagulant

3
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Risk of mixing drugs that PROLONG QT interval with antipsychotics

Torsades de Pointes (TdP), a potentially fatal heart arrhythmia that can lead to sudden cardiac death.

4
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What are anticholinergic effects that may be accompanied by an antipsychotic?

Think DRYING

  • Flushing

  • Dry mouth

  • Mydriasis (dialated pupils)

  • Alt mental statu

  • Increased HR

  • Urine retention

  • Tremor

  • HTN