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Ketone Bodies, Bile Salts and Cholesterol
Ketone Bodies, Bile Salts and Cholesterol
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1
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What is the net gain of ATP from the complete oxidation of palmitic acid (C16) through β-oxidation and TCA cycle?
106 ATP.
2
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How many acetyl CoA molecules are formed from the complete oxidation of palmitic acid?
7 acetyl CoA.
3
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During β-oxidation of palmitic acid, how many cycles are involved?
7 cycles.
4
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What are the three main types of ketone bodies produced?
Acetoacetate, acetone, and β-hydroxybutyrate.
5
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What condition generally leads to the production of ketone bodies?
Increased fat oxidation due to low glucose levels or unmet energy requirements.
6
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Why are ketone bodies considered important during fasting or diabetes?
They serve as an energy source for muscles and the brain when glucose is low.
7
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What percentage of bile salts is typically reabsorbed in the enterohepatic cycle?
> 90% of bile salts.
8
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What is the primary function of cholesterol?
To make bile, steroid hormones, and to serve in cell membranes.
9
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What is the dietary recommendation for cholesterol intake?
Less than 300 mg/d.
10
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Where are bile salts produced and stored?
Produced in the liver and stored in the gallbladder.
11
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What happens to bile salts that are not reabsorbed in the ileum?
About 0.5 g is lost in feces per day.
12
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What is the role of soluble fibers in relation to bile salts?
They bind to bile and promote its excretion.