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alcohol
hepatic issues, peripheral neuropathy, myopathy, wernicke’s encephalopathy, korsakoff’s psychosis, cardiomyopathy, GI issues/inflammation, leukopenia, thrombocytopenia, and sexual dysfunction
sedative/anxiolytic/hypnotic
depressed CNS, respiratory, CV, renal, hepatic, and thermoregulation
stimulant
adrenergic effects
inhalant
neuro/CNS damage, respiratory issues, GI effects, and renal failure/toxicity
opioid
drowsy, euphoric, decreased GI motility, constipation, and hypotension
hallucinogen
adrenergic and increased psychological effects