Studied by 0 people
Looks like no one added any tags here yet for you.
What does short-term plasticity look like?
Use- dependent changes in synaptic transmission lasting for milliseconds to minutes
What forms of short-term plasticity are there?
- Facilitation (shortest)
- Depression
- Augmentation
- Post-tetanic potentiation (longest)
Short-term vs Long term plasticity
Why study synaptic plasticity in Aplysia
Simple nervous system (large neurons)
Mapping neuronal circuits is easy
What does the gill withdraw in Aplysia show?
Behavioural plasticity
What does Behavioural plasticity Is seen in Aplysia?
Habituation
Sensitization: long-term or short-term
What does the circuit responsible for the gill withdrawal reflex consist of?
An excitatory interneuron and motor neuron innervating the gill muscle
What does repeated touch to siphon cause?
Habituation due to reduction of neurotransmitter release at SN/MN synapse
What does sensitization involve?
Another sensory neuron which synapses onto modulatory interneuron
What does the activation of modulatory seotonergic neuron lead to?
Potentiates transmission at SN synapses
What is the mechanism of short-term sensitization?
SLIDE
What is the mechanism of long-term sensitization?
SLIDE
Note 
Flashcard (21)