Bone marrow transplantation
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7 Terms
What is the purpose of hematopoietic stem cell (bone marrow) transplantation?
It is used to replace malfunctioning or improperly developed cells in a patient’s bone marrow.
What types of conditions is bone marrow transplantation used to treat?
It is used to treat hematopoietic cell cancers.
What is done to the patient's bone marrow before transplantation?
The patient’s bone marrow is destroyed using chemotherapy and irradiation before transplantation.
What can mutations in critical genes affect in hematopoietic cells?
Mutations can affect blood cell development and function.
What conditions are associated with the erythroid lineage?
Thalassemia and sickle cell anemia are associated with the erythroid lineage.
What conditions are associated with the lymphoid lineage?
Immunodeficiencies are associated with the lymphoid lineage.
How does bone marrow transplant help recipients?
It provides genetically unaltered stem cells capable of giving rise to normally functioning red or white blood cells.
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