Bone marrow transplantation

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7 Terms

1
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What is the purpose of hematopoietic stem cell (bone marrow) transplantation?

It is used to replace malfunctioning or improperly developed cells in a patient’s bone marrow.

2
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What types of conditions is bone marrow transplantation used to treat?

It is used to treat hematopoietic cell cancers.

3
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What is done to the patient's bone marrow before transplantation?

The patient’s bone marrow is destroyed using chemotherapy and irradiation before transplantation.

4
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What can mutations in critical genes affect in hematopoietic cells?

Mutations can affect blood cell development and function.

5
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What conditions are associated with the erythroid lineage?

Thalassemia and sickle cell anemia are associated with the erythroid lineage.

6
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What conditions are associated with the lymphoid lineage?

Immunodeficiencies are associated with the lymphoid lineage.

7
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How does bone marrow transplant help recipients?

It provides genetically unaltered stem cells capable of giving rise to normally functioning red or white blood cells.