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autonomic nervous system
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Autonomic nervous system (ANS)
division of the peripheral nervous system located throughout the body that controls involuntary functions by regulating cardiac muscle, smooth muscle, and glands to maintain homeostasis
Visceral reflex arc
pathway involving receptors in organs, sensory neurons, integration in the central nervous system, and autonomic motor output that produces automatic responses in internal organs
Preganglionic neuron
neuron with cell body in the brainstem or spinal cord whose axon travels to an autonomic ganglion where it synapses with another neuron to relay signals
Postganglionic neuron
neuron with cell body in an autonomic ganglion whose axon extends to cardiac muscle, smooth muscle, or glands to produce a response
Autonomic ganglion
cluster of neuron cell bodies in the peripheral nervous system where synapses occur between preganglionic and postganglionic neurons to relay autonomic signals
Somatic motor pathway
single neuron pathway from the central nervous system to skeletal muscle that produces voluntary movement without synapsing in a ganglion
Autonomic motor pathway
two neuron pathway involving preganglionic and postganglionic neurons that synapse in a ganglion before reaching target organs to control involuntary activity
Short axon (autonomic)
nerve fiber found in neurons located close to their synapse point where distance to next structure is minimal due to ganglion placement
Long axon (autonomic)
nerve fiber found in neurons that must travel farther distances due to ganglion location relative to spinal cord or target organ
Sympathetic preganglionic neuron
neuron with cell body in lateral horn of T1-L2 spinal cord whose short axon travels through ventral root and white ramus to synapse in sympathetic ganglia
Sympathetic postganglionic neuron
neuron with cell body in chain or collateral ganglia whose long axon travels to target organs to produce stress responses
Sympathetic chain ganglia
paired ganglia located along both sides of the vertebral column that receive input from preganglionic neurons and distribute signals to postganglionic neurons
Collateral ganglia
ganglia located anterior to the vertebral column near the abdominal aorta that receive splanchnic nerve input and send signals to abdominal and pelvic organs
Splanchnic nerves
nerves carrying preganglionic fibers from thoracic spinal cord through chain ganglia to collateral ganglia for synapsing
White ramus communicans
branch containing myelinated preganglionic sympathetic fibers that connect spinal nerves to sympathetic chain ganglia
Gray ramus communicans
branch containing unmyelinated postganglionic sympathetic fibers that return to spinal nerves to reach target tissues
Acetylcholine (ACh)
neurotransmitter released by all preganglionic neurons and some postganglionic neurons that binds to cholinergic receptors to transmit signals
Norepinephrine (NE)
neurotransmitter released by most sympathetic postganglionic neurons that binds to adrenergic receptors to activate stress responses
Epinephrine (Epi)
hormone released from adrenal medulla into bloodstream that enhances sympathetic effects by binding to adrenergic receptors throughout the body
Adrenergic receptor
receptor on target cells of cardiac muscle, smooth muscle, and glands that binds norepinephrine or epinephrine to produce sympathetic effects
Alpha 1 receptor
receptor on smooth muscle that causes contraction when activated leading to effects like vasoconstriction
Alpha 2 receptor
receptor that regulates neurotransmitter release and modulates sympathetic activity
Beta 1 receptor
receptor on cardiac muscle that increases heart rate and contraction strength when activated
Beta 2 receptor
receptor on smooth muscle that causes relaxation such as bronchodilation in airways
Beta 3 receptor
receptor involved in fat metabolism and energy regulation in adipose tissue
Adrenal medulla
inner region of adrenal gland composed of modified neurons that release epinephrine and norepinephrine into blood when stimulated by sympathetic input
Chromaffin cells
modified postganglionic neurons in adrenal medulla that release hormones into bloodstream instead of using synapses
Sympathetic activation
state in which signals increase heart rate, dilate airways, reduce digestion, and mobilize energy to prepare for stress
Parasympathetic preganglionic neuron
neuron with cell body in brainstem or sacral spinal cord whose long axon travels to ganglia near or within target organs
Parasympathetic postganglionic neuron
neuron with cell body in ganglia near or in target organs whose short axon delivers signals directly to tissues
Parasympathetic ganglion
ganglion located near or within target organs where synapse occurs between preganglionic and postganglionic neurons
Cholinergic receptor
receptor on neurons or target cells that binds acetylcholine and mediates parasympathetic or ganglionic signaling
Nicotinic receptor
receptor located on postganglionic neurons in autonomic ganglia that binds acetylcholine and causes depolarization
Muscarinic receptor
receptor located on target organs that binds acetylcholine and produces parasympathetic effects
Parasympathetic activation
state in which signals decrease heart rate, increase digestion, stimulate gland secretion, and promote energy storage
Hypothalamus
brain region in the diencephalon that integrates autonomic functions and maintains homeostasis by controlling both divisions
Reticular formation
network in the brainstem that processes autonomic signals and helps regulate vital functions like heart rate and breathing
Amygdala
brain structure involved in emotional processing that influences autonomic responses through connections with hypothalamus
Cerebral cortex
outer brain region that can influence autonomic activity through conscious thought and decision making
Autonomic centers
regions in hypothalamus and brainstem that coordinate and regulate involuntary body functions
Dual innervation
condition where most organs receive input from both sympathetic and parasympathetic divisions allowing balanced regulation of function