PART IVD: LAB TEST (ANEMIA)

Hypo-proliferative

[Types of Anemia] Marrow Failure; Aplastic Anemia

Hypo-proliferative

[Types of Anemia] Renal Failure

Hypo-proliferative

[Types of Anemia] Iron Deficiency

Aplastic Anemia

sever marrow aplasia/ pancytopenia

Aplastic Anemia

may caused by Chloramphenicol, Felbamate, Phenylbutazone

Aplastic Anemia

bone marrow does not produce enough blood cells

Renal Failure

no sufficient erythropoetin

Iron Deficiency

caused by blood loss, and malabsorption; S & S include restless leg syndrome, frequent headache, increased cold sensitivity, brittle nails, hair loss, depression, SOB, and fatigue and tiredness

Defective Nuclear Maturation

[Types of Anemia] Megaloblastic Anemia

Defective Nuclear Maturation

[Types of Anemia] Pernicious Anemia

Megaloblastic Anemia

caused by Vitamin B12/ folate deficiency

Pernicious Anemia

under mergaloblastic anemia; a specific type of M.A. resulting from the body's inability to absorb B12 due to lack of intrinsic factor

Increased Destruction

[Types of Anemia] Hemolytic Anemia

Hemolytic Anemia

RBCs are destroyed faster than the bone marrow; can be caused by inherited conditions: Sickle cell Anemia, Thalassemia, G6P deficiency

Coombs Test

detects Ab coating RBCs and Ig against RBCs

Acetaminophen, Methyldopa, Chlorpromazine, Ibuprofen, Procainamide, Interferon alpha, Antibiotic (Cefalexin, Ceftriaxone, Penicillin, Ampicillin/Methicillin)

[Drugs that can cause Hemolytic Anemia] A Mad Cat Is Playing Really Intense Antibiotics

Abnormal Production/Destruction

[Types of Anemia] Sickle Cell Anemia

Sickle Cell Anemia

blood flow restriction that causes sickle shape

Abnormal Production/Destruction

[Types of Anemia] Thalassemia

Thalassemia

shape of blood cells are malformed

Sickle Cell Anemia

inherited hemoglobin disorder characterized by (-) charged hemoglobin

Thalassemia

heterogenous group of genetic disorders resulting from a decreased synthesis of alpha/ beta chains of hemoglobin