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Major Groups of Microorganisms
Categories including Bacteria, Fungi, Algae, Protozoa, and Viruses based on their characteristics and habitats.
Characteristics of Microbes
Microscopic size, diverse environments, rapid reproduction, unicellular or multicellular, and metabolic diversity.
Roles of Microbiologists
Tasks like researching microbial physiology, studying pathogens, developing antibiotics, and working in environmental and industrial microbiology.
Importance of Microbes
Essential for nutrient cycling, decomposition, symbiotic relationships, biotechnological applications, and bioremediation.
Eukaryotes vs
Comparison of eukaryotic cells with nucleus and organelles to prokaryotic cells without nucleus, highlighting differences in complexity and size.
Evolutionary Time of Microbes
Microbes' ancient existence around 3.5 billion years ago and their fundamental role in biosphere development.
Theory of Evolution
Explanation of life diversity through natural selection and genetic variation, emphasizing rapid evolution in microbes.
Importance of Decomposition by Fungi & Bacteria
Significance of recycling nutrients and breaking down organic matter in ecosystems.
Uses of Microorganisms
Applications in producing antibiotics, enzymes, hormones, fermentation, waste treatment, and bioremediation.
Bioremediation
Utilizing microorganisms to clean up contaminated environments like oil spills and heavy metals.
Genetic Engineering
Manipulating genes to create genetically modified organisms for beneficial purposes, such as GM yeast for ethanol production.
Compounds from GMO
Products like yeast for fermentation, TPA for thrombolytic action, monoclonal antibodies, and bacterial strains for bioremediation.
Recombinant DNA
DNA molecules formed by combining genetic material from different sources in laboratory settings.
Examples of Diseases from Microorganisms
Diseases caused by bacteria (Tuberculosis, Cholera), viruses (Influenza, HIV), fungi (Candidiasis, Athlete's foot), and protozoa (Malaria, Amoebiasis).
Communicable vs
Distinction between infectious diseases that can be transmitted and non-transmissible diseases like diabetes.
Examples of Infectious Diseases
Common infectious diseases such as Influenza, Tuberculosis, HIV/AIDS, and Malaria.
Differentiate among Bacteria, Archaea, and Eukaryotic
Comparison of prokaryotic bacteria and archaea with eukaryotic organisms based on cell structure and characteristics.
What do Fungi Produce?
Outputs like enzymes, antibiotics (penicillin), and alcohol (yeast fermentation).
Termination
The process ends when a stop codon is reached, and the newly formed protein is released.
Rifampicin
Inhibits RNA polymerase, blocking transcription.
Tetracycline
Binds to the 30S subunit of the ribosome, preventing the attachment of aminoacyl-tRNA.
Chloramphenicol
Binds to the 50S subunit of the ribosome, inhibiting peptide bond formation.
Erythromycin
Binds to the 50S subunit of the ribosome, preventing translocation during protein synthesis.
Streptomycin
Binds to the 30S subunit, causing misreading of mRNA.
Mutation
A change in the DNA sequence that can have various effects on an organism.
Frameshift Mutation
Insertion or deletion of nucleotides that changes the reading frame of the gene.
Nonsense Mutation
A change that converts a codon into a stop codon, resulting in premature termination of translation.
Silent Mutation
A change in the DNA sequence that does not alter the amino acid sequence of the protein.
Missense Mutation
A change that results in the substitution of one amino acid for another in the protein.