Carbon Dioxide Transport

what does O2 and CO2 bind to

O2= heme Co2=globin

what percentage of CO2 is transported

7%

what percentage of CO2 is diffused into RBC

93%

what percentage of the 93% is chemically combined with Hb

23%

why is venous blood blue

because of CO2 binding

what percentage of the 93% is voncerted to HCO-3

70%

law of mass action

every reaction in body is reversible and the direction depends on how much substrates are available

haldane effect

CO2 loaded on Hb, affinity Hb + O2 low (tissues)

O2 loaded on Hb, affinity Hb + CO2 (lungs)

bohr effect

H+ formed CO2, H+ binds to Hb, affinity Hb + Oz low (tissue)

Oz binds to Hb, affinity Hb + H low (lungs)

why do we breath

to maintain blood/plasma pH levels

why isn’t breathing like your heart breathing

not autorhythmic (skeletal muscles), controlled by motor neurons and central pattern generator

what do chemoreceptors pick up

ions and molecules

where is the central chemorecpetor

brain

where are the peripheral chemoreceptors

carotid and aorta (same a barorecpetors)

what is the only thing to cross BBB

gas CO2 and O2

where is H+ detected

centrally

where is CO2 and O2 detected

peripherally

in healthy people what gas controls breathing

CO2

people with lung disease what controls breathing

O2