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Respiratory System Function
To obtain oxygen and eliminate carbon dioxide. Provides an area for gas exchange
Upper Respiratory System
Includes the nose, nasal cavity, sinuses, and pharynx. Functions to cleanse, warm, and humidify the air
Lower Respiratory System
Includes the larynx, trachea, bronchi, bronchioles, and alveoli.
Conducting Zone
Passages that serve only for airflow; no gas exchange occurs here. Also known as anatomical dead space
Respiratory Zone
Passageways and structures (respiratory bronchioles, alveoli) that participate in gas exchange
External Respiration
Exchange of O2 and CO2 between the atmosphere and body tissues
Internal Respiration
The use of oxygen within mitochondria to generate ATP (cellular respiration)
Nasal Conchae (Turbinates)
Bony scrolls in the nasal cavity that help cleanse, warm, and humidify the air
Respiratory Epithelium
Pseudostratified ciliated columnar epithelium with mucus-secreting goblet cells
Pharynx (Overall)
Common passageway shared by the digestive and respiratory systems
Pharynx Regions
Nasopharynx (air only), Oropharynx (air, food, drink), and Laryngopharynx (air, food, drink)
Larynx (Voice Box)
Primary functions are sound production and keeping food and drink out of the airway
Thyroid Cartilage
The largest laryngeal cartilage; shield-shaped structure that forms the Adam’s Apple
Glottis
The slit-like opening in the larynx that inhaled air leaves through
Epiglottis
Flap of tissue that covers the glottis during swallowing to deflect food into the esophagus
Trachea (Windpipe)
Straight tube whose walls contain C-shaped cartilage rings to keep the lumen open. Bifurcates at the carina
Primary Bronchi
One per lung. The Right primary bronchus has a larger diameter and a steeper angle
Right Lung Lobes
Has 3 lobes: superior, middle, and inferior
Left Lung Lobes
Has 2 lobes: superior and inferior. Contains the cardiac notch (indentation for the heart)
Bronchioles
Small air passages that lack supportive cartilage. They contain smooth muscle to control air flow
Bronchodilation
Increase in the luminal diameter, caused by sympathetic activation (e.g., epinephrine release)
Respiratory Bronchioles
The thinnest, most delicate passages and the beginning of the respiratory zone (gas exchange starts here)
Alveoli
Air sacs in the lung; the site of gas exchange with blood capillaries. Lined by simple squamous epithelium
Type I Alveolar Cells
Simple squamous cells that form the sites of gas diffusion.
Type II Alveolar Cells
Cells responsible for producing surfactant
Surfactant
A fluid that decreases surface tension of the lung, which helps prevent the alveoli from collapsing
Parietal Pleura
The outer membrane that lines the pleural cavity wall
Visceral Pleura
The membrane that covers the lungs directly
Pleural Fluid
Contained in the pleural cavity; reduces friction as the membranes slide on one another
Primary Inspiratory Muscles
Diaphragm and external intercostal muscles
Aging Respiratory System
Elastic tissue deteriorates (reducing inflation/deflation ability) and movement of the rib cage is restricted
Emphysema
Disorder characterized by damaged and permanently enlarged alveoli, leading to inadequate surface area for gas exchange
Asthma
Inflammatory disease characterized by bronchial inflammation, spasms, and excessive mucus production that make breathing difficult