Apoptotic and Anti-Apoptotic Summary Table
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Last updated 2:51 AM on 3/19/26
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6 Terms
1
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What are the pro-apoptotic effector proteins?
Bax, Bak
2
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What is the function of the pro-apoptotic effector proteins?
Execute apoptosis by forming membrane pores
3
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What are the anti-apoptotic proteins?
BCL‑2, BCL‑XL, BCL‑W
4
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What is the function of the anti-apoptotic proteins?
Block Bax/Bak; maintain mitochondrial integrity
5
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What are the pro-apoptotic BH3-only proteins?
Bad, Noxa, Puma, Bim, Bid
6
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What is the function of the pro-apoptotic BH3-only proteins?
Sense stress and promote Bax/Bak activation
