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Chemical Digestion
Breaks down food into monomers so they can be absorbed into the bloodstream
Mechanical Digestion
The physical breakdown of food into smaller pieces
Mouth Digestion
Capable of both mechanical and chemical digestion
Salivary Amylase
Enzyme in saliva that converts starches into simple sugars
Parotid Glands
The largest salivary glands, located in the cheeks
Submandibular Glands
Salivary glands located under the jaw
Sublingual Glands
Salivary glands located under the tongue
Esophagus
A transport tube for food; no digestion occurs here
UES and LES
Upper and Lower Esophageal Sphincters that regulate food passage
Parietal Cells
Stomach cells that produce Hydrochloric Acid (HCl)
Function of HCl
Denatures proteins and changes the shape of molecules in food
Chief Cells
Stomach cells that produce the inactive enzyme Pepsinogen
Activation of Pepsin
Pepsinogen becomes active pepsin when exposed to HCl
Pepsin
The active stomach enzyme responsible for digesting protein
Stomach Anatomy
Includes the Cardia, Fundus, Body, Antrum, and Pylorus
Pyloric Sphincter
The valve at the bottom of the stomach regulating exit to the duodenum
Duodenum
The first part of the small intestine where the majority of digestion occurs
Jejunum
The middle part of the small intestine where the majority of absorption occurs
Ileum
The final section of the small intestine ending at the ileocecal valve
Bile
Produced by the liver and stored in the gallbladder to help digest fats
Pancreatic Amylase
Enzyme in pancreatic juice that breaks starches into sugars
Trypsin
Enzyme in pancreatic juice that breaks proteins into amino acids
Pancreatic Lipase
Enzyme in pancreatic juice that breaks triglycerides (TGs) into fatty acids
Nuclease
Enzyme in pancreatic juice that breaks DNA into nucleotides
Brush Border Enzymes
Digestive enzymes installed on the surface of cells in the GI tract
Small Intestine Surface Area
Increased by plicae circulares, villi, and microvilli
Large Intestine Absorption
Primarily absorbs water, Vitamin K, and electrolytes (Na, K)
Vitamin K Production
Produced by bacteria within the large intestine
Colon Path
Cecum -> Ascending -> Transverse -> Descending -> Sigmoid
Haustra
The small pouches or segments of the colon
Anal Sphincters
Internal and external sphincters that control the timing of defecation
Gastric Juice Electrolytes
Highest source of Chloride (Cl-) loss (125 mEq/L)
Bile/Pancreatic Electrolytes
Highest sources of Sodium (Na+) loss (140-150 mEq/L)
Diarrheal Stool Electrolytes
Major source of high Potassium (K+) loss (50++)