Module 0 Review: Biological Aging and Scientific Posters

Flashcards covering key concepts in biological aging, nematode life cycles, and elements of scientific posters.

What is biological aging?

The process of gradual decline in physiological functions that occurs over time.

List three different aging hallmarks and explain their biological pathways.

1. Mitochondrial dysfunction - involves ATP production and damage from reactive chemicals. 2. Telomere attrition - shortening of telomeres leading to cell death signals. 3. Dysbiosis - imbalance of gut bacteria affecting digestion and immunity.

What is deregulated nutrient sensing in the context of aging?

Pathways involved in cell and tissue building that, when reduced, can extend lifespan.

What cellular changes are associated with genomic instability?

Changes caused by external agents that reduce DNA repair mechanisms, leading to genomic changes.

What does mitochondrial dysfunction result in?

Loss of organelle function, leading to leakage of reactive oxygen species and cell death.

What is the life stage of nematodes that comes directly after the egg?

Larva (specifically Larval stage 1 or L1).

What are the main sections of a scientific poster?

Introduction, Results, Conclusions, and Hypothesis.

What information does the introduction section of a scientific poster provide?

Relevance and reasoning behind the research being performed.

Why is C. elegans considered a good model organism for studying aging in humans?

They have genes orthologous to human aging genes, short lifespan, low growing costs, and various research tools.