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carbohydrate role
used as fuel to drive processes throughout the body by converting glucose into ATP
protein role
form cellular and tissue-level structures. components of many chemicals in the body
lipid role
key part of cell membrane, act as signaling molecules, major fuel source
nutrient breakdown in GI tract (mechanical)
chewing of food into a bolus, swallowing and entering stomach, peristalsis mixes and softens food to create chyme, pylorus acts as a filter for pyloric sphincter, intestines work to mix and absorb food
what impacts enzyme function?
temperature and pH
monosaccharides
glucose, fructose, galactose, ribose, deoxyribose
disaccharides
sucrose, lactose, maltose
sucrose
glucose and fructose
lactose
glucose and galactose
maltose
two of glucose
polysaccharides
starches, glycogen, cellulose
building blocks of proteins
amino acids
nutrient breakdown in GI tract (chemical)
salivary amylase starts breaking down carbohydrates, fundus stores undigested food and gases, food mixes with acidic chyme and starts breaking down, protein breaks down due to HCl and pepsin, stomach contents enter duodenum, intestinal and stomach juices facilitate absorption in small intestine, large intestine secretes mucus
salivary amylase
site of origin: salivary glands
action: break down polysaccharides into smaller polysaccharides
pancreatic amylase
site of origin: pancreas
action: break down smaller polysaccharides into disaccharides and monosaccharides
alpha-dextrinase
site of origin: brush border (SI)
action: breaks down alpha-dextrins into monosaccharides
sucrase
site of origin: brush border (SI)
action: breaks down sucrose into glucose and fructose
lactase
site of origin: brush border (SI)
action: breaks down lactose into glucose and galactose
maltase
site of origin: brush border (SI)
action: breaks down lactose into glucose and galactose
pepsin
site of origin: chief cells
action: break down polypeptides into smaller polypeptides
trypsin
site of origin: pancreas
action: break down smaller polypeptides into dipeptides and amino acids
aminopeptidase
site of origin: brush border (SI)
action: break down smaller polypeptides into amino acids and smaller polypeptides
dipeptidase
site of origin: brush border (SI)
action: break down dipeptides into amino acids
lingual lipase
site of origin: salivary glands
action: breaks down lipids into glycerol and fatty acids
gastric lipase
site of origin: chief cells
action: breaks down lipids into glycerol and fatty acids
pancreatic lipase
site of origin: pancreas
action: breaks down lipids into glycerol and fatty acids
enzyme function
catalysts on biological processes
GI tract organs
mouth, pharynx, esophagus, stomach, small intestine, large intestine, rectum, anus
accessory organs
teeth, tongue, salivary glands, liver, gallbladder, pancreas
absorption
uptake of a substance
desiccation
removing water
secretion
release of a substance
mechanical digestion
breakdown of chunks of food into smaller bits of the same food
chemical digestion
breakdown of macronutrients (by enzymes/acid) into smaller molecules
ingestion
consumption via mouth
mastication
chewing
deglutition
swallowing
propulsion
pushing/moving forward
peristalsis
waves of smooth muscle contraction that causes propulsion
defecation
expelling feces from GI tract
churning
method of mechanical breakdown
segmentation
mechanical breakdown in intestines, breaking food into “segments” as well as mixing
bolus
rounded mushy lump of food
chyme
liquified food
feces
found in colon
layers of digestive tract
mucosa (superficial), submucosa, muscularis extrema, serosa (deep)
mucosa layers
epithelium (stratified squamous), lamina propria, muscularis mucosae
muscularis externa layers
inner circular, outer longitudinal
myenteric plexus function
controls peristalsis and other contractions of muscularis externa
submucosal plexus function
controls muscularis mucosae and glandular secretions of mucosa
parietal peritoneum
covers abdomen
visceral peritoneum
covers organs
mesentery
holds small intestine to posterior abdominal wall
mesocolon
holds large intestine to posterior abdominal wall
falciform ligament
binds liver to anterior abdominal wall
greater omentum
layer of fat that loosely covers transverse colon and small intestine
lesser omentum
connects medial curve of stomach and liver
upper esophageal sphincter
regulates swallowing reflex and keeps excess air out of esophagus when not in use
lower esophageal sphincter
prevents reflux of contents from stomach
stomach layers
inner oblique (innermost), middle circular, outer longitudinal
cardia
interface between esophagus and stomach
fundus
holds both undigested food and gases released during digestion
body
main portion of stomach where most churning and digestion takes place
pyloric antrum and canal
holds the broken down food until it is ready to be released into small intestine
pyloric sphincter
keeps contents in stomach until liquified and regulates slow release of chyme
parietal cells
secrete HCl and intrinsic factor
chief cells
secrete pepsinogen and gastric lipase
G cells
secrete gastrin into the blood stream
regions of small intestine
duodenum, jejunum, ileum
small intestine ways to absorb
plicae circularis, villi, microvilli
regions of large intestine
cecum, ascending/transverse/sigmoid colon, rectum, anal canal, anus
internal anal sphincter
smooth muscle, involuntary
external anal sphincter
skeletal muscle, voluntary
hard palate
bony, forms most of roof of mouth
soft palate
muscular, forms rest of mouth’s roof
uvula
prevents swallowed food from entering nasal cavity
cheek
forms lateral wall of oral cavity
molars
grind food
premolars
crush and grind food
canines
tear food
incisors
cut food
superior labial frenulum
attaches superior lip to gum
tongue
forms floor of mouth, manipulates food for chewing and swallowing, shaoes food, senses taste
lingual frenulum
limits movement of tongue posteriorly
gingiva
cover tooth sockets and help anchors teeth
inferior labial frenulum
attaches inferior lip to gum
enamel
protects tooth from wear and tear, made of calcium salts
dentin
makes up majority of tooth, calcified connective tissue
pulp cavity
contains pulp (connective tissue containing nerves and blood vessels)
cementum
bone-like substanxe that attaches the rooth to the periodontal ligament
periodontal ligament
helps anchor tooth to underlying bone
apical foramen
opening at base of root canal through which blood vessels, lymphatic vessels, and nerves enter a tooth
salivary glands
parotid gland (cheek), submandibular gland (jaw), sublingual gland (tongue/under mouth)
intrinsic salivary glands
scattered throughout mouth, always producing saliva. minor
extrinsic salivary glands
3 pairs of glands, major
salivary gland histology
serous cells (watery fluid, enzyme), mucous cells (mucous), duct cells (form ducts leading to oral cavity)
hepatic triad
branch of hepatic portal vein, branch of hepatic artery proper, bile ductule
liver
produces bile
gallbladder
stores and concentrates bile
pancreas histology
islets of langerhans (endocrine), acini (exocrine)