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Hydroxl
Polar

Methyl
Nonpolar

Carbonyl
Polar

Carboxyl
Charged ionized to release H+, acidic

Amino
Charged, accepts H+ to form NH3, basic

Phosphate
Ionizes release H+ (P) , acidic

Sulfyanl
Moderatley Polar

pH= Pka
50% pronated
pH<Pka
Pronated (H+ dominates)

pH>Pka
depronated, A- doms
