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SCID
adenosine deaminase deficiency that can be treated with gene therapy/bone marrow transplant
Lesch-Nyhan Syndrome
fatal defect in purine salvage
Antibiotics
Sulfanilamide & Trimethoprim inhibit tetrahydrofolate (THF) pathways in bacteria
Gout
Buildup of uric acid in the blood can be reduced by allopurinol
Azaserine
Glutamine analog that inhibits purine biosynthesis
Fluorouracil
Inhibits thymidylate synthase
Methotrexate
Inhibits dihydrofolate reductase (M)
Aminopterin
Inhibits dihydrofolate reductase (A)