Complement System Disease
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9 Terms
Complement System
Very efficient weapon against infection by
amplifying phagocytosis
C3a and C5a
Receptors for these complements have been found in coronary plaques
C2 deficiency
Most common Complement Deficiency
Atherosclerosis
Recurrent Streptococcal and Staphylococcal infections
Lupus like syndrome
C2 deficiency will lead to these diseases
MBL
important during the interval between the loss of passively acquired maternal antibodies and the ability of infants to produce their own antibody
Pneumonia
Sepsis
Meningococcal disease in infants
Lack of MBL will lead to these diseases
C3 deficiency
most severe type
Large scale gram negative infection
Tissue Necrosis
Hemolysis
Complement can be harmful if this factors is present
Hereditary deficiency of Complement
Increased susceptibility to infection. Delayed clearance of immune complexes.
Note 
Flashcards (56)