Functional Genomics & Methods

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Last updated 4:01 AM on 3/25/26
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10 Terms

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Transposon Mutagenesis

Disrupt genes to study function

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RB-TnSeq

Barcoded transposon sequencing method

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Mutant Fitness

Growth relative to wild type

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Gain of Function

Adding gene to study effect

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High-Throughput Screening

Large-scale protein/gene analysis

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Barcoded Library

Collection of uniquely tagged mutants

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RB-TnSeq Goal

Measures mutant fitness using barcodes.

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Barcoded Library

Collection of uniquely tagged mutants.

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Price et al. (2018)

Studied unknown gene functions.

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High-Throughput Analysis

Large-scale protein function analysis.

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