Classification of Mutant Alleles

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5 Terms

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amorph

null allele (lost all function)

loss of function alleles

2
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hypomorph

weak allele (lost some function)

loss of function allele

3
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hypermorph

overactive

gain of function allele

4
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antimorph

dominant negative (lost all normal activity and prevent the normal protein from working)

gain of function allele

5
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neomorph

new function

gain of function allele