Reactivity Profiles as Bases/Nucleophiles

0.0(0)
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
Card Sorting

1/14

encourage image

There's no tags or description

Looks like no tags are added yet.

Study Analytics
Name
Mastery
Learn
Test
Matching
Spaced

No study sessions yet.

15 Terms

1
New cards

NaOH

Unhindered, Strong Base (H2O = 16 > 12), Strong Nucleophile (O- and unhindered)

2
New cards

H2O

Unhindered, Weak Base (H3O + = -2.5 < 12), Weak Nucleophile (positive)

3
New cards

Alcohols (CH3OH), (CH3CH2OH)

Unhindered, Weak Base (OH+ = -2.5 < 12), Weak Nucleophile (positive O)

4
New cards

CH3CH2ONa

Unhindered, Strong Base (when it gains a proton, the negative on the oxygen turns neutral, and neutral O = pka 16 > 12), Strong Nucleophile (O- and unhindered)

5
New cards

NaH

Unhindered, Strong Base (MEMORIZE - know that CA has a high pKa), Strong Nucleophile (negative charge on Hydrogen)

6
New cards

NaNH2

Unhindered, Strong Base (neutral N = 38), Strong Nucleophile (negative N, unhind)

7
New cards

NH3(1)

unhindered, Weak Base (Positive N = 10 < 12), Weak Nucleophile (neutral N)

8
New cards

NaSH

(memorized), Unhindered, Strong Base, Strong Nucleophile (negative S, unhind)

9
New cards

(CH3)3COH

Hindered! (tert-butyl), Weak Base (O+= -2.5 < 12), Weak Nucleophile (hindered)

10
New cards

(CH3)3COK

Hindered! (tert-butyl), Strong Base (neutral O = 16 >12), Weak Nucleophile (hindered)

11
New cards

LDA LiN(i-Pr)2

Hindered! (LDA), Strong Base (neutral N = 38 > 12), Weak Nucleophile (hindered)

12
New cards

CH3CO2Na

(memorize) CARBOXYLATE: Unhindered, WEAK base, Strong Nucleophile

13
New cards

CH3CO2H

Unhindered, Weak Base (Positive O = -2.5 < 12), Weak Nucleophile (neutral O)

14
New cards

KCN

unhindered, Weak Base (MEMORIZE), Strong Nucleophile (negative, unhind)

15
New cards

NaCCH

Unhindered, Strong Base (MEMORIZE), Strong Nucleophile (negative C, unhind)