foundations exam ii -- lapinsky
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14 Terms
acidic functional groups
carboxylic acid/carboxylate
beta-dicarbonyl
imide
sulfonamide
sulfonylurea
phenol
sulfonic acid
phosphoric acid
acidic hydrogen atoms
the hydrogen that is “popped off” an acidic functional group
active site of an enzyme
where the substrate would bind to the enzyme in order for an effect to occur
ADME
main determinants of pharmacokinetic properties
ADME acronym
absorption, distribution, metabolism, elimination
adverse drug reaction
unwanted side effects of a drug
alicyclic
carbon ring w/o aromaticity
aliphatic
carbon chain that is not an aromatic ring
ambulatory care
outpatient medical care
diphenhydramine
1st gen anti-histamine
certirizine
2nd gen anti-histamine
aromatic ring
compound that is cyclic, flat, w/ fully conjugated delocalized pi electrons
follows Huckel’s rule (4n+2) pi electrons
basic functional groups
amines (incl. alicyclic)
imine
amidine
guanidine
hydrazine
aniline
imidazole
quinoline
beta-adrenergic receptor agonists
