Yersinia Pesitis

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7 Terms

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Shape

Bipolar Pin Appearance

Cocco Baccilus

Pleomorphic

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Characteristics

Obligate Pathogen

The Black Death (Dead End Host)

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Transmission

Potential Biological Weapon (aerosols)

Zoonotic : ( Xenopsylla)

flea - coagulase - block…- hungry flea - human bloodT

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Agar

Giemsa Stain or Wayson’s

Facultative Anaerob

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Target

PMN - Macrophage

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V.F.

Coagulase in flea : Plasminogen - Activating Protease

Fraction 1 : capsular protein 37 C

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Pathogenesis

Meningitis

Necrotic Lymph Node (one)

Hemorrhagic inflammation (pneumonia plaque)

Plagues:

Bubonic: LN swollen= neck,grain,axilia: Buboes

Septicemia: Meningitis & Sepsis

Pneumonic: can lead to hemorrhage mediastinitis (1& 2)