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Endocrine system role in metabolism
Regulates metabolism through hormones released by endocrine glands.
Hypothalamic-Pituitary Axis (HPA)
System that regulates hormone production throughout the endocrine system.
Insulin
Hormone that allows cells to take in glucose and prevents excessive breakdown of glycogen in the liver and muscles.
Glucagon
Hormone that increases blood glucose by signaling the liver to release stored glucose.
Myxedema
Severe hypothyroidism characterized by swelling and thickening of the skin.
Trousseau sign
Spasms caused by inflating a blood pressure cuff; indicates hypocalcemia.
Chvostek sign
Facial muscle twitching when the facial nerve is tapped; indicates hypocalcemia.
Metabolism
Collection of biochemical reactions in body cells that produce energy, repair cells, and maintain life.
Digestive system role in metabolism
Processes nutrients from food and transports them to cells for energy and cellular functions.
Hormones
Chemical messengers released by endocrine glands that regulate metabolism, growth, reproduction, and other body processes.
Hypothalamus
"Master switchboard" that receives signals from nervous and endocrine systems.
Pituitary gland
"Master gland" that controls the release of many hormones.
Pineal gland
Produces melatonin and regulates sleep-wake cycles.
Thyroid gland
Produces T3 and T4 hormones that increase metabolism.
Thymus
Stimulates production and maturation of T lymphocytes.
Adrenal glands
Produce corticosteroids and help the body respond to stress.
Pancreas endocrine function
Produces insulin and glucagon to regulate blood glucose levels.
Ovaries
Produce estrogen and progesterone to regulate the menstrual cycle.
Testes
Produce testosterone and regulate sperm production.
Primary functions of the endocrine system
Regulate metabolism, growth, development, reproduction, mood, blood glucose, and stress response.
Kidneys endocrine function
Release renin to regulate blood pressure.
GI tract endocrine function
Supports digestion and regulates energy balance.
Liver endocrine role
Metabolizes carbohydrates, proteins, and lipids and detoxifies substances.
Skin metabolic role
Assists with metabolism and excretes waste through sweating.
Heart endocrine role
Helps regulate blood pressure and fluid balance.
Adipose tissue endocrine role
Stores energy and communicates with organs through hormone signals.
Metabolic disorder cause
Too much or too little hormone production disrupting homeostasis.
Common metabolic disorders
Diabetes, obesity, osteoporosis, thyroid disorders, cirrhosis, Addison's disease, and Cushing syndrome.
Risk factors for metabolic disorders
Genetics, environmental factors, obesity, autoimmune disorders, tumors affecting endocrine glands.
Hemoglobin A1C normal range
Less than 5.7%.
Prediabetes A1C range
5.7-6.4%.
Diabetes A1C range
Greater than 6.4%.
Normal fasting blood glucose
70-100 mg/dL.
Prediabetes fasting glucose
100-125 mg/dL.
Diabetes fasting glucose
Greater than 126 mg/dL.
Normal sodium range
135-145 mEq/L.
Normal potassium range
3.5-5.0 mEq/L.
Normal calcium range
9-11 mg/dL.
Normal magnesium range
1.7-2.2 mEq/L.
Normal phosphate range
2.5-4.5 mg/dL.
Normal cholesterol level
Less than 200 mg/dL.
Nursing assessment for metabolic disorders
Obtain history, perform focused assessment, evaluate skin, hair, nails, thyroid, motor function, and sensory function.
Health promotion for metabolism
Maintain healthy weight, exercise regularly, attend follow-up appointments, take medications as prescribed, and reduce stress.
Collaborative therapies for metabolic disorders
Hormone replacement therapy, oral glucose agents, thyroid medications, physical therapy, dietitian consultation, and counseling.
Complementary therapies for metabolism
Acupuncture, meditation, yoga, massage, and nutritional supplements.
Most common metabolic disorder in pregnancy
Gestational diabetes.
Risks of gestational diabetes
Macrosomia, breathing problems in newborn, and increased risk of C-section.
Common metabolic disorders in older adults
Type 2 diabetes, hypothyroidism, and osteoporosis.
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