Pharmacology exam II

Classifications of antidepressants

Tricyclic antidepressants

MAO inhibitors

Selective serotonin reuptake inhibitors

Serotonin norepinephrine inhibitors

Tricyclic antidepressants

Imipramine

Amitriptyline

Clomipramine

TCA unicorns

Risk of suicidality in younger patients

Serotonin syndrome with MAOI

Serotonin syndrome

Agitation, hallucinations, seizure, hyperthermia, coma, hypertension, tachycardia

Monoamine oxidase inhibitors

Phenelzine

Isocarboxazid

Selegiline

MAOI unicorns

Fatal hypertensive crisis

Risk of serotonin syndrome with TCA/SSRI

Selective serotonin reuptake inhibitors

Fluoxetine

Sertraline

Paroxetine

Citalopram

SSRI unicorns

Serotonin syndrome with MAOI

Toxicity with TCAs, SNRIs, st. john’s wort, triptan

Serotonin norepinephrine inhibitors

Duloxetine

Venlafaxine

SNRI unicorns

Serotonin syndrome with MAOI, TCA, SSRI, or other serotonergics

Risk for bleeding with ASA, NSAIDs, or other coagulation meds

Other antidepressants

Bupropion

Mirtazapine

Trazodone

Mental disorders treated by antipsychotics

Schizophrenia

Bipolar disorder

Narcolepsy

Attention deficit disorders

Typical antipsychotics

Haloperidol

Prochlorperazine

Chlorpromazine

Typical antipsychotics unicorns

Severe cardiac dysrhythmias (prolonged QT)

Increased risk of death with dementia

Risk for neuroleptic syndrome (hyperpyrexia, muscle rigidity, AMS, autonomic instability)

Atypical antipsychotics

Clozapine

Aripiprazole

Olanzapine

Ziprasidone

Risperidone

Ziprasidone unicorn

Fatal skin reactions & diabetes

Bipolar medications for mania

Lithium

Lithium unicorn

Serum levels greater than 2.5 is a significant risk for death

Drugs for ADHD/narcolepsy

Methylphenidate

Armodafinil

Modafinil

Atomoxetine

Drugs for ADHD/narcolepsy unicorn

Dependency risk