Cannabis Pscyhopharmacology

0.0(0)
studied byStudied by 0 people
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
Card Sorting

1/9

encourage image

There's no tags or description

Looks like no tags are added yet.

Study Analytics
Name
Mastery
Learn
Test
Matching
Spaced

No study sessions yet.

10 Terms

1
New cards

Metabolite

a substance used or made during metabolism  

2
New cards

urine testing for THC

focuses on identification of carboxy-THC, which is only slowly excreted

3
New cards

CBD

  • antagonist at cannabinoid receptors

  • less psychedelic effect, but therapeutic use

  • forensic testing doesn’t look for CBD in urine because it isnt psychoactive

  • CBD undergoes first pass metabolism

  • “ attracted a surge of interest when a high-CBD, low-THC strain of marijuana appeared to help reduce convulsions in a case of epilepsy

4
New cards

THC (tetrahydrocannabinol)

  • partial agonist at cannabinoid receptors

  • anandamine is natural neurotransmitter @ cannabinoid recpetors

5
New cards

cannabiniods (the psychoactive chemical compounds found in marijuana) effects in the brain

bind to cb1 receptors concentrated in brain structures like

  1. hippocampus - learning & memory

  2. frontal lobe - attention & judgement

  3. amygdala - fear and anxiety

  4. basal ganglia & cerebellum - movement

  5. hypothalamus - ingestion

  6. ventral striatum - drug high

  7. brain stem & spinal cord - vomiting reflex

6
New cards

THC effects on memory

affects all 3 stages of memory processing

  1. encoding

  2. consolidation

  3. retrieval

  • effects caused by CB1 receptors in hippocampus

  • abnormally low blood flow to every area of the brain

  • disruption of focus

7
New cards

theraupatic applications of cannabonids = sativex and multiple sclerosis

  • THC & CBD can protect aginst pain & inflammation

  • spasticity (can reduce this) in multiple sclerosis

  • Sativex = THC & CBD mouth spray medication for muscle spams and sleep quality associated with multiple sclerosis

8
New cards

cannabinoids

chemical compounds found in marijuana

9
New cards

theraupatic applications of cannabonids = epilepsy

  • medical marijuana for epilepsy

  • charlottes webb - cannabis for Dravet Syndrome (Charoltte Figi case)

  • CBD to THC ratio of 30:1

  • Epidiolex (CBD in liquid solution, taken by mouth) for Lennox-Gastaut syndrome

10
New cards

THC steps in the brain

  1. inhibitory neurotransmitters are active in synapse and preventing dopamine from being released

  2. THC binds to cannabinoid receptors in the presynaptic neuron or postsynaptic neuron on synapse

  3. THC mimics neurotransmitter anandamide

  4. dopamine is squirted into synapse

  5. anandamide breaks down faster (makes you calm), and doesn’t give a high