Heredity
the transmission of traits from one generation to the next by inheriting DNA from a single parent (asexual reproduction) or from two parents (sexual reproduction)
Chromosomes
the packed and organized structures of DNA found in cells
Eukaryotic chromsome
consists of a single molecule of DNA wrapped around proteins called histones
Histones
function to package and organize the DNA
Linked
genes that are located on the same chromosome
Linear shape
the shape of eukaryotic DNA
Bivalent chromosomes
chromosomes that consist of 2 copies of the original chromomsome
Centromere
the structure that holds chromatids together at the center
Chromatids
two copies of a chromosome
Autosomes
chromosomes that are not involved in gender determination
Sex chromosomes
chromosomes that are involved in the process of gender determination
Prokaryotic chromosome
circular DNA shape
Nucleoid
the region in the cell where prokaryotic DNA is found
Plasmid
a small, circular, double-stranded DNA molecule that is distinct from a cell’s chromosomal DNA
Conjugation
the process where plasmids can be exchanged between bacterial cells
Gene
a segment of DNA which codes for a single polypeptide or protein
Genome
an organism’s complete set of DNA
Haploid
refers to cells that have only one copy of each type of chromosome
Dipolid
cells that have two copies of each type if chromosome
Locus
the location of a gene on a chromosome
Asexual reproduction
reproduction that involver one parent and produces genetically identical daughters
Sexual reproduction
reproduction that involves 2 parents and produces genetically different offspring
Meiosis
a specialized type of nuclear division that reduces the chromosomes number by half, creating four haploid cells genetically distinct from the parent cell
Prophase I
the homologous chromosomes condense and become visible as the x shape pair up and exchange genetic information by crossing over
Homologous chromosomes
Chromosomes of the same type/number
Synapsis
the pairing of 2 chromosomes
Crossing over
the physical exchanging of segments of DNA
Metaphase I
the two members of each homologous pair of bivalent chromosomes align on each side of the metaphase plate
Anaphase I
one member of each homologous pair of chromosomes is pulled toward each pole of the cell by the microtubules of the spindle apparatus
Telophase I
the homologous chromosome pairs reach the poles of the cell, the spindle fibers disappear, nuclear envelopes form around each set of chromosomes
Interkinesis
a short interphase-like period that occurs between meiosis I and meiosis II
Prophase II
Similar to prophase II and no synapis or crossing over occurs during this stage
Metaphase II
the chromosomes in both cells become arranged on the metaphase plate
Anaphase II
the centromeres of each chromosome (in both cells) separate and the sister chromatids move towards opposite poles of the cell
Telophase II
a nuclear envelope forms around each set of chromosome and cytokinesis occurs producing 4 haploid daughters
Spermatogensis
the process of sperm creation
Oogenesis
the process of egg creation
Nondisjunction
the failure of homologous chromosomes or sister chromatids to separate properly during cell division
Aneuploidy
results in daughter cells with abnormal chromosome numbers
Karyotype
a picture of a person’s chromosomes
Chromosomal mutations
large chunks of chromosomes (but not entire chromosomes) are affected
Duplication
a chromosome ends up with two or more copies of a gene segment
Deletion
a chromosome ends up with no copies if a particular gene segment
Inversion
a chromosomal region is flipped around so that it points in the opposite, wrong direction
Translocation
a piece of one chromosome is attached to another non-homologous chromosome
Gregor Mendel
the “Father of Genetics”; groundbreaking work with inheritance in pea plants
Law of Dominance
when parents with pure, contrasting traits are crossed together, only one form of the trait appears in the next generation
Law of Segregation
states that alleles segregate randomly into gametes
Law of Independent Assortment
alleles of 2 or more different genes get sorted into gametes independently of one another
Trait
a genetically determined characteristic
Alleles
refers to different versions of a gene
Doninant
more likely to be expressed
Recessive
less likely to be expressed
Homozygous
an organism is said to be homozygous or pure bred for a trait if the two alleles it possesses for the trait identical (TT or tt)
Heterozygous
an organism is said to be heterozygous or a hybrid for a trait if the two alleles is possesses for the trait are different (Tt)
Phenotype
refers to the physical traits or appearance of an organism
Genotype
refers to an organism’s genetic (DNA) make-up for a trait
Punnet Square
a chart which shows the possible genotypic outcomes for a mating cross based on the parent’s genotype
Monohybrid Cross
a cross in which only one trait is analyzed
Dihybrid Cross
a cross in which the inheritance of two traits is analyzed at the same time
Linked genes
occur on the same chromosome, and therefore, tend to be inherited together
Incomplete dominance
a form on intermediate inheritance in which one allele for a specific trait is not completely expressed its paired allele
Codominance
a condition in which both alleles in a pair are expressed at the same time
Multiple alleles
when 3 or more alternative forms of a gene (allele) can occupy the same locus
Pleiotropy
a condition in which one gene affects multiple (seemingly unrelated) characteristics
Epistasis
a condition in which a gene at one locus affects a gene at a second locus
Polygenic Inheritance
occurs when a trait is governed by two or more sets of alleles
Multifactorial traits
those controller by multiple genes that are also affected by physiological and environmental influences
Lethal alleles
certain allele combinations which are lethal and prevent the birth of individuals with certain genotypes
Pedigree chart
a diagram showing the lineage or genealogy of an individual and all the direct ancestors, usually to analyze or follow the inheritance of trait
Mode of Inheritance
the manner in which a genetic trait or disorder is passed from one generation to the next
Autosome
a non-sex chromosome
X & Y chromosomes
sex chromosomes
Carrier
an individual who possesses only one copy of a recessive allele
Gene linkage
genes are linked if they are found on the same chromosome
Phenotypic plasticity
occurs when individuals with the same genotype exhibit different phenotypes in different environments