Activity 1: Sole of foot (thick skin)

Tissue subtype for epidermis

Keratinized stratified squamous epithelium

General tissue class for dermis

connective tissue

Tissue subtype for hypodermis

loose adipose connective tissue

Tissue subtype for all epidermal strata

Keratinized stratified Squamous epithelium

Keratinocytes

• Stratum (or strata) location: S. Basale, S. Spinosum, S. Lucidum, S. Granulosum, S. Corneum.

• Function: Produce fibrous Keratin (protein that gives skin its protective properties)

• major cells of epidermis tightly connected to desmosomes

• millions slough off every day

Melanocytes

• Stratum (or strata) location: S. Basale

• Function: Produce pigment melanin , which is packaged into melanosomes. Melanosomes are transferred to keratinocytes where they help protect Keratinocytes nucleus from UV damage.

Dendritic (Langerhans) cells

• Stratum (or strata) location: S. Spinosum, S. Basale

• Function: Star shaped macrophages that patrol deep epidermis, are key activators of immune system.

Tactile (Merkel) cells

• Stratum (or strata) location : S. Basale

• Function: sensory receptors that sense touch.

Tissue subtype for papillary layer of dermis

loose areolar connective tissue (CT)

Tissue subtype for reticular layer of dermis

Dense irregular connective tissue

Function of fibroblasts

Elasticity, repair, and maintaining skin structure

Function of collagen fibers

Prevent wrinkles, provide tensile strength and firmness.