BB

IHTR
DHTR
FNHTR
TRALI
Sepsis
AlloImmunization
Acute GVHD

FEVER

IHTR
FNHTR
Sepsis
PCITR
TRALI

CHILLS/RIGOR

DHTR
hemosiderosis

Jaundice

FNHTR
TACO

TACHYCARDIA

FNHTR
ATR
PCITR

NAUSEA/VOMITING

UTR
ATR

PRURITIS

ATR
TRALI

DYSPNEA

TRALI
TACO

CYANOSIS

TRALI
TACO

PULMONARY EDEMA

FNHTR
TACO

HYPERTENSION

TACO
PCITR

ANXIETY

IHTR

Pain or Discharge at the infusion site

IHTR

back or flank pain,

IHTR
ATR
TRALI

hypotension

IHTR

, epistaxis

IHTR

hemoglobinuria

IHTR

DIC

IHTR

renal failure.

DHTR
Alloimmunization

Low Hemoglobin

DHTR

Spherocyte

FNHTR

tachypnea

UTR

Wheals

UTR

erythema

TRALI

Hypoxia

TRALI

Non-productive cough,

TRALI

non-productive cough,

Sepsis

increase in body temperature of more than 2°C

PCITR

Numbness

PCITR

Cardiac arrhythmia

PCITR

Tingling

PCITR

Altered respirations,

Alloimmunization

Decreased hematocrit

Alloimmunization

platelet refractories.

PTP

Thrombocytopenia

Alloimmunization
PTP

Bleeding

Acute TA GVHD

diffuse skin rashes

Acute TA GVHD

diarrhea

Acute TA GVHD

abnormal liver function,

Acute TA GVHD

Pancytopenia

Chronic TA GVHD

Scleroderma-like disease,

Chronic TA GVHD

Sicca syndrome,

Chronic TA GVHD

Interstitial pneumonitis,

Chronic TA GVHD

Malabsorption

Hemosiderosis

Muscle weakness, fatigue

Hemosiderosis

Weight loss

Hemosiderosis

Mild diabetes

Hemosiderosis

Growth retardation in children

IHTR

equate renal perfusion.

Diuretics

Treat shock and manage DIC

DHTR

Give antigen-negative blood for subsequent transfusions.

FNHTR

Administer antipyretic.
For rigors, treat with meperidine.

UTR

Administer antihistamine.

ATR

Treat with epinephrine, IV corticosteroids and oxygen therapy.

TRALI

Give respiratory support, steroids, and diuretics.

TACO

Stop the transfusion

Administer diuretics.

Place the patient in upright position.

Sepsis

Give intravenous antibiotics, fluids, and vasopressors to maintain blood pressure.

PCITR

The management is directed at correcting the underlying cause of the signs and symptoms.

Alloimmunization

Treatment depends on the type and severity of the transfusion reaction.

PTP

Use corticosteroids, therapeutic plasma exchange, and intravenous immunoglobulin.

TA GVHD

Treat with immunosuppressive medications.

Hemosiderosis

Oral iron chelators