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two basic components of all tissues
cells and extracellular matrix
high cellularity
high cells, low extracellular matrix
four main tissue types and their principal functions
epithelial tissue - covering, form lining of internal structures and glands
connective tissue - support
muscle tissue- movement, heat production
nervous tissue- control, communication
epithelial tissue general characteristics
-cells arranged in continuous sheets (single or multiple layers)
-cells closely packed and held tightly together (high cellularity)
-found at a boundary between two different environments (interface)
two general types of epithelium
1-covering and lining epithelium
>covers outer surfaces, lines inner surfaces
2-glandular epithelium
>forms most glands of the body
>sweat, oil, milk, pituitary
epithelium general functions
protection of underlying tissues, barriers, regulate things
secretion
absorption
diffusion
filtration
sensory reception
special features of epithelia
high cellularity
specialized contacts: proteins used to hold cells together (bc a lot)
polarity: apical(free), basal
support by connective tissue
avascular: no direct blood supply, no capillaries
nervous innervation: usually vessels and nerves are together, but not here
regeneration: healing, lives at dangerous, innerface locations prone to damage
basement membrane
has 2 layers: the basal lamina (secreted by epithelium) and reticular lamina (part of the underlying connective tissue)
classifications of epithelial
simple: one layer of cells
stratified: several layers of cells
squamos: flat, thinnest in body
cuboidal: same size all around
columnar: taller than they are wide
some might have cilia and be ciliated
simple squamos epithelium
single layer of flattened cells, disc-shaped nuclei, sparse cytoplasm
function: diffusion and filtration of materials
location: kidneys, air sacs of lungs, lining of heart, blood vessels, lymphatic vessels, lining of ventral body cavity
when SSE forms a serous membrane, it is mesothelium
simple cuboidal epithelium
single layer of cubelike cells, large spherical nuclei
function: secretion and absorption
location: kidney tubules, ducts and secretory portions of small glands, ovary surface
tightly packed rings
simple columnar epithelium
single layer of tall cells, round to oval nuclei, may contain goblet cells (mucus secreting), may have cilia
function: absorption, secretion of mucus and enzymes, ciliated type propels mucus
location: nonciliated type lines digestive tract (stomach to anus), gallbladder, and excretory ducts of some glands; ciliated type lines small bronchi, uterine tubes, and some areas of uterus
pseudostratified columnar epithelium
single layer of cells of differing heights, some not reaching free surface; may have goblet cells and cilia
function: secretion of mucus, propulsion of mucus
location: nonciliated type in sperm carrying ducts and ducts of large glands, ciliated type lines trachea and most of upper respiratory tract
type of simple columnar with more
all cells touch basement membrane
stratified squamos epithelium
thick membrane composed of several cell layers; basal cells are cuboidal or columnar; surface cells are squamos; in keratinized type, surface cells are full of keratin and dead; basal cells produce cells of more superficial layers
function: protects underlying tissues in areas subjected to abrasion
location: nonkeratinized type forms moist linings of esophagus, mouth, vagine; keratinized type forms epidermis of skin, a dry membrane
name based on shape at apical surface
stratified cuboidal epithelium
generally two layers of cubelike cells
function: protection
location: largest ducts of sweat glands, mammary glands, and salivary glands
makes a ring and it’s two layers
stratified columnar epithelium
several cell layers; basal cells usually cuboidal; superficial cells elongated and columnar
function: protection, secretion
location: rare in body, small amounts in male urethra and in large ducts of some glands
tight junctions
seal cells together to form a fluid barrier, prevents molecules from passing through intercellular space
prevent paracellular transport (b/w cell)
desmosomes (anchoring junctions)
hold cells together that are under mechanical stressors
bind adjacent cells together and help form an internal tension-reducing network of fibers
like teeth on a zipper interlock
gap junctions
communicating junctions allow ions and small molecules to pass from one cell to the next for intercellular communication
tubular components of cells fuse together
basal lamina
part of the basement membrane, but sometimes these labels are interchangeably
free space and nuclei
apical surface features of epithelium
microvilli ( non-motile and function to increase surface area at apical area) and cilia (function to move things along the surface of a cell)
actin filaments make up microvilli; PM covers entire outside of actin microfilament
microtubules make up individual cilia
glands
epithelia that make and secrete a product form glands
secretions are aqueous fluids that usually contain proteins
-hormones
-mucous
-sweat and oils
-bild and digestive enzymes
-milk
endocrine glands
secretions=hormones
hormones are released directly into ECF and then diffuse into blood stream w/o a duct
effector organs are far away
exocrine glands
secretions flow onto body surfaces or into cavities
secretions act locally, effector organ is nearby
multicellular: multiple cells form a gland that secretes product via a duct
unicellular: one-celled gland