NURS 472A Exam 3 Week 12

Cimetidine (Tagamet)

Class

Cimetidine (Tagamet)

Class

• TC

  • Antiucler Drugs

• PC

  • Histamine2 (H2) Receptor Antagonists

Omeprazole (Prilosec)

MOA

irreversible inhibition of H+, K+ - ATPase (proton pump)

Omeprazole (Prilosec)

ADEs

• fractures

• pneumonia

• rebound acid hyper-secretion

Sucralfate (Carafate)

Class

• TC

  • Antiulcer Drugs

• PC

  • Mucosal Protectant

Calcium Carbonate (Tums)

Class

• TC

  • Antacids

• PC

  • Acid Neutralizers

Calcium Carbonate (Tums)

Indication

• peptic ulcer disease

• GERD

Magnesium (Hydroxide)

Class

• TC

  • Antacids

• PC

  • Acid Neutralizers

Methylcellulose (Citrucel)

Class

• TC

  • Laxatives

• PC

  • Bulk-Forming

Methylcellulose (Citrucel)

Indication

constipation

Methylcellulose (Citrucel)

ADEs

• esophageal obstruction

• intestinal obstruction/impaction

Docusate Sodium (Colace)

MOA

lowers surface tension of stool

Docusate Sodium (Colace)

ADEs

• dehydration

• diarrhea

Bisacodyl (Dulcolax)

ADEs

• highly abused

• dehydration

• diarrhea

Ondansetron (Zofran)

MOA

• blocks type 5-HT receptors in CTZ

• blocks afferent vagal neurons in upper GI tract

Ondansetron (Zofran)

ADEs

• prolongation of QT interval

• headache

• diarrhea

• dizziness

Scopolamine (Transderm Scop)

Class

• TC

  • Drugs for Motion Sickness

• PC

  • Muscarinic Antagonist

Scopolamine (Transderm Scop)

Indication

• motion sickness

• production of cycloplegia

• mydriasis for ophthalmic procedures

Loperamide (Imodium)

Class

• TC

  • Antidiarrheals

• PC

  • Opioid Agonists

Sulfasalazine (Azulfidine)

Class

• TC

  • Drugs for IBD

• PC

  • 5 - Aminosalicylates

Sulfasalazine (Azulfidine)

Indication

• ulcerative colitis

• Crohn’s disease

Metoclopramide (Reglan)

ADEs

• sedation

• diarrhea

• tardive dyskinesia (involuntary movement in face)

Ursodiol (Actigall)

Class

• TC

  • Drugs for Gallstones

• PC

  • Ursodeoxycholic Acid

Ursodiol (Actigall)

Indication

Cholelithiasis

• hardened deposits of digestive fluid that can form in gallbladder