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Heredity
The transmission of traits from one generation to the next.
Genetics
The scientific study of heredity and hereditary variation.
Genes
A discrete unit of hereditary information consisting of a specific nucleotide sequence in DNA (or RNA, in some viruses).
Gametes
A haploid reproductive cell, such as an egg or sperm. Unite during sexual reproduction to produce a diploid zygote.
Somatic cells
Any cell in a multicellular organism except a sperm or egg or their precursors.
Locus
A specific place along the length of a chromosome where a given gene is located.
Asexual reproduction
The generation of offspring from a single parent that occurs without the fusion of gametes (by budding, division of a single cell, or division of the entire organism into two or more parts). In most cases, the offspring are genetically identical (clones) to the parent.
Sexual reproduction
A type of reproduction in which two parents give rise to offspring that have unique combinations of genes inherited from both parents via the gametes.
Life cycle
The generation-to-generation sequence of stages in the reproductive history of an organism
Karyotype
A display of the chromosome pairs of a cell arranged by size and shape; taken during the metaphase stage of cell division because chromosomes are at their most condensed and aligned, making them clearly visible, distinct, and easy to photograph and analyze as short, thick structures
Homologous chromosomes
A pair of chromosomes of the same length, centromere position, and staining pattern that possess genes for the same characters at corresponding loci. One of these is inherited from the organism’s father, the other from the mother.
Sex chromosomes
A chromosome responsible for determining the sex of an individual.
Autosomes
A chromosome that is not directly involved in determining sex; not a sex chromosome.
Diploid cell
A cell containing two sets of chromosomes (2n), one set inherited from each parent.
Haploid cells
A cell containing only one set of chromosomes (n)
Fertilization
The union of haploid gametes to produce a diploid zygote.
Zygote
The diploid cell produced by the union of haploid gametes during fertilization; a fertilized egg.
Meiosis
A modified type of cell division in sexually reproducing organisms consisting of two rounds of cell division but only one round of DNA replication. It results in cells with half the number of chromosomes the original cell + half the amount of DNA in the original cell
Alteration of generations
A life cycle in which there is both a multicellular diploid form, the sporophyte, and a multicellular haploid form, the gametophyte; characteristic of plants and some algae.
Meiosis I
The first division of a two-stage process of cell division in sexually reproducing organisms that results in cells with half the number of chromosome sets as the original cell.
Meiosis II
The second division of a two-stage process of cell division in sexually reproducing organisms that results in cells with half the number of chromosome sets as the original cell; very similar to mitosis (ignoring the difference in chromosome number)
Synaptonemal complex
A zipper-like structure composed of proteins, which connects two homologous chromosomes tightly along their lengths during part of prophase I of meiosis.
Synapsis
The pairing and physical connection of duplicated homologous chromosomes during prophase I of meiosis; allows for crossing over (genetic recombination) to occur thru this connection, creating new gene combinations that increase genetic diversity.
Recombinant chromosomes
A chromosome created when crossing over combines DNA from two parents into a single chromosome.
Gametophyte
In organisms (plants and some algae) that have alternation of generations, the multicellular haploid form that produces haploid gametes by mitosis. The haploid gametes unite and develop into sporophytes.
Sporophyte
In organisms (plants and some algae) that have alternation of generations, the multicellular diploid form that results from the union of gametes. Produces haploid spores by meiosis that develop into gametophytes.
Crossing over
The reciprocal exchange of genetic material between nonsister chromatids during prophase I of meiosis, as DNA molecules of nonsister chromatids are broken by proteins and are rejoined to each other. In humans, generally occurs at least 1-3 times per chromosome pair.
Chiasma
The X-shaped, microscopically visible region where crossing over has occurred earlier in prophase I between homologous nonsister chromatids. Become visible after synapsis ends, with the two homologs remaining associated due to sister chromatid cohesion.
Nonkinetochore microtubules
Microtubules that don't attach to chromosomes but are crucial for pushing the cell poles apart, elongating the cell during anaphase, and maintaining the overall structure and integrity of the mitotic spindle, ensuring proper cell division and genetic separation
Kinetochore microtubules
The essential link between chromosomes and the mitotic spindle, serving to attach to centromeres, generate forces for chromosome movement (pulling and pushing) through polymerization/depolymerization (of tubulin subunits), align them at the metaphase plate, and ensure their equal segregation into daughter cells during cell division; these shorten in length during anaphase as nonkinetochore microtubules elongate
Kinetochore
A structure of proteins attached to the centromere that links each sister chromatid to the mitotic spindle.
Sister chromatid cohesion
The crucial process that physically links identical sister chromatids together from their creation during DNA replication (S phase) until their separation in anaphase, mediated by protein complexes called cohesins, ensuring proper chromosome alignment and segregation into daughter cells during mitosis and meiosis, and also playing roles in DNA repair.
Each chromosome pairs with homolog and crossing over occurs, microtubules from one pole or the other attach to the kinetochores, microtubules move homologous pairs toward the metaphase plate
3 Unique Characteristics of Prophase I
During prophase I, duplicated homologs pair up, and crossing over occurs; at metaphase I of meiosis pairs of homologs are positioned at the metaphase plate; at anaphase I, the duplicated chromosomes of each homologous pair move toward opposite poles while sister chromatids of each duplicated chromosome remain attached.
3 events unique to meiosis that occur during meiosis I (think of prophase I, metaphase I, and anaphase I)
Pairs of homologous chromosomes are arranged at the metaphase plate facing opposite poles, in turn the chromatid pairs of each homolog face opposing poles/attach to opposing kinetochore microtubules, the chromosome pairs line up randomly at the plate
Unique Characteristic of Metaphase I (what lines up? how are they oriented?)
Breakdown of cohesin rings allows homologs to separate and move toward opposite poles, sister chromatid cohesion persists at the centromere causing chromatids to move as a unit toward the same pole, nonkinetochore microtubules elongate as kinetochore microtubules shorten via the depolymerization of tubulin subunits
3 Unique Characteristics of Anaphase I
Each half of the cell has a complete haploid set of duplicated chromosomes, each chromosome is composed of two sister chromatids, cleavage furrow forms, chromosomes decondense and nuclear envelopes form
4 Unique Characteristics of Telophase I and Cytokinesis
Independent Assortment of Chromosomes
A process unique to meiosis where homolog pairs line up randomly during Metaphase I of meiosis, ensuring that alleles for different genes segregate independently into gametes (sperm/egg), creating genetic diversity by mixing maternal and paternal chromosomes in unique combinations. This randomness in alignment, coupled with crossing over, means inheriting a specific allele for one trait doesn't predict the allele for another, generating vast combinations in offspring.
Plants exhibit alternation of generations, meaning they have two multicellular stages: a diploid sporophyte that produces haploid spores by meiosis, and a haploid gametophyte that produces gametes by mitosis.
Describe the life cycle of plants (cellular stages, type of life cycle)
Animals have a diplontic life cycle, in which the organism is multicellular and diploid for most of its life; meiosis produces haploid gametes, and there is no multicellular haploid stage.
Describe the life cycle of animals (cellular stages, type of life cycle)
Fungi typically have a haplontic life cycle, where the main multicellular stage is haploid; haploid cells fuse during fertilization to form a brief diploid stage that immediately undergoes meiosis to produce haploid spores.
Describe the life cycle of fungi (cellular stages, type of life cycle)
Spores
A reproductive unit, often a single cell with a protective wall, that develops into a new organism without fusing with another cell, differing from gametes. These are key to the asexual reproduction and dispersal of many organisms, including fungi, plants (like ferns/mosses), algae, and protozoa, allowing survival in harsh conditions before germination
Cohesin
a vital ring-shaped protein complex that acts like molecular glue, holding duplicated sister chromatids together after DNA replication to ensure they separate correctly during cell division