MHC presentation and adaptive immunity

What does the adaptive immune use to see and respond to molecules in pathogens

antigens

The best types of antigens are those that do not ______ components with the host

share

Lymphocyte receptors do not actually bind to the antigen they instead bind to the __________ within the antigen

epitope

B cell receptors recognize epitopes based on their __________ unlike T cells

3d structure

T cell receptors recognize antigens based on their __________ unlike B cells

Peptide sequence

An antigen cannot be recognized by T lymphocytes unless it is bound to a __________

MHC complex

having a lot of diversity in MHC molecules is good but it runs the risk of initiating ___________

auto immunity

MHC 1 expresses _________ to _____ cells

• intracellular pathogens

• CD8 T cells

MHC 1 expresses ________ to ______ cells

• extracellular pathogens

• CD4 T cells

which of the MHC complexes is expressed in every cell

MHC 1

What are the 3 stages of antigen presentation

1. Antigen uptake

2. antigen processing

3. antigen presentation

What cells act as professional antigen presenting cells

• dendritic cells

• macrophages

What MHC complex is only presented via professional antigen presenting cells

MHC 2

What cells are considered lymphocytes

• T cells

• B cells

• NK cells

The space where lymphocytes undergo initial maturation programming and differentiation are considered ______ lymphoid organs

primary

What are the 2 primary lymphoid organs in the animal

• Thymus

• bone marrow

clonal selection theory states that every T and B cell recognize one unique _________

epitope

When encountering its antigen the first thing a lymphocyte does is ___________

multiply

during multiplication both B and T cells create 2 types one active and one not what are their names

• effector cells

• memory cells